Primary Aromatic Amines (PAAs) are substances that are used, for example, in the production of certain colorants, so-called azo pigments, notably in the color range yellow – orange – red. Whereas a large number of PAAs are safe for human health, some PAAs are known human carcinogens. For kitchenware, paper napkins, baker’s bags with colorful print and other printed items that come in contact with food, some PAAs may pose a health risk, if they are transferred to the food. Because of the potential health risks, specific migration limits (SMLs) have been put in place.
In this application note we describe a sensitive LC-MS/MS method for the analysis of 23 common PAAs with very easy sample preparation. The Xevo TQ-S micro provides sensitive detection levels well below the regulation on plastics (EU 10/2011).