Exploring the Benefits and Potential of iKey Microfluidic Chromatography and Time-of-Flight Mass Spectrometry for Pesticide Residue Analysis

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Michael McCullagh, Severine Goscinny, Vincent Hanot, Richard Tyldesley Worster, and David Douce
Waters and Wetenschappelijk Instituut Volksgezondheid Institut Scientifique de Santé Publique
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Application Notes
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Application Notes
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This study aims to characterize sensitivity enhancements and reduction of matrix suppression for residue analysis. IonKey/MS offers some unique advantages for profiling complex matrices. Sensitivity enhancements enable sample dilution and hence matrix suppression reduction in residue screening assays, while maintaining data quality. It may be possible to reduce the need to closely matrix match QC samples to the test samples by introducing large sample dilution factors to negate the matrix load and thus benefit from efficiency savings within routine surveillance monitoring.

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