Protein Columns

Protein Analyses and Lab Scale Purifications

The development and successful commercialization of protein-based biopharmaceuticals and diagnostic reagents frequently depends on the ability to adequately characterize these complex biomolecules. Waters columns and methods can help solve your protein separation and characterization challenges.

Waters technology utilizes reversed-phase, ion-exchange, hydrophilic-interaction, and size-exclusion chromatography modes for peptide separation applications such as the analysis and purification of synthetic peptides, the characterization of complex proteolytic digests, and bioanalysis. These orthogonal separation techniques help provide the critical characterization data and isolated material required to produce the next generation drug.

 


HILIC for Large Biomolecules It is now possible to use HILIC to glean previously unattainable information from intact proteins (with or without glycosylation), protein fragments, and complex, released glycans.
Protein Hydrophobic Interaction Chromatography (HIC) Columns Functionalized with a butyl ligand coating and are well suited for the characterization of proteins and biotherapeutics including monoclonal antibodies (mAb) and antibody drug conjugates (ADC).
SEC 컬럼 분석용 SEC(크기 배제 크로마토그래피) 컬럼은 응집체, 단량체 및 조각 분석에 이상적입니다. Waters SEC 컬럼을 사용하여 용액에서 크기별로 생체 분자를 분리하십시오.
단백질 역상 컬럼(Protein Reversed-Phase Columns) TFA나 FA와 같은 이온쌍 시약을 사용하는 단백질 역상 크로마토그래피는 상대적인 소수성 차이에 따라 단백질 혼합물을 분리하는 용도로 사용할 수 있습니다.
단백질 이온 교환 컬럼 (Protein Ion-Exchange Columns) 이온 교환 크로마토그래피는 표면의 전하 차이를 이용해 단백질을 분리하는 기법으로 단백질 정제와 분석에 모두 사용됩니다.
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A Platform Method for Protein SEC
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