Vitamin Testing Solutions

Vitamin Testing Solutions

Implement cost-effective methods for vitamin testing across a range of food and beverage products with Waters standardized and reliable workflows. Waters solutions provide separation and detection capabilities to accelerate time to results, protect consumers and brands, and ensure the accuracy of product label claims.

Implement cost-effective methods for vitamin testing across a range of food and beverage products with Waters standardized and reliable workflows. Waters solutions provide separation and detection capabilities to accelerate time to results, protect consumers and brands, and ensure the accuracy of product label claims.
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Vitamin c effervescent tablet is dissolving in glass of water
Vitamin c effervescent tablet is dissolving in glass of water

Overview

Ensuring that the vitamin content of products is consistent with the label claim isn’t just good practice – it’s a regulatory requirement. Waters recognizes the crucial role that rapid, reliable, and cost-effective analytical methods play in accurately monitoring nutritional content and ensuring compliance with product labels.

Waters vitamin solutions enable food and beverage testing laboratories to create efficient testing methods, supporting manufacturers in:

  • Standardizing analysis for a range of complex water- and fat-soluble vitamins
  • Testing for multiple vitamins across a range of food and beverage products
  • Minimizing overages of vitamins and other raw products
  • Reducing the number of methodologies required
  • Rapidly confirming nutritional value for vitamin specifications and label compliance
Rows of bottled juices or sports drinks

Applications

Fat-soluble vitamin analysis is complicated by matrix complexity and the thermal instability of compounds, as well as a lack of standardized methods for differentiating natural from synthetic vitamins. Waters innovative solutions, including the ACQUITY UPC2 System and multi-dimensional liquid chromatography, overcome these challenges by enhancing solubility and stability, improving efficiency, and offering cost-effectiveness in routine quality control environments.

Fat-soluble vitamin analysis is complicated by matrix complexity and the thermal instability of compounds, as well as a lack of standardized methods for differentiating natural from synthetic vitamins. Waters innovative solutions, including the ACQUITY UPC2 System and multi-dimensional liquid chromatography, overcome these challenges by enhancing solubility and stability, improving efficiency, and offering cost-effectiveness in routine quality control environments.

Application Notes

Vitamin K in wooden spoon with bottle of tablets and green herbs

The analysis of water-soluble vitamins is complicated by matrix complexity, metal-analyte interaction, and sensitivity issues. Waters HPLC systems facilitate this through robust methods that enhance reproducibility and accuracy across different platforms, simplifying method transfer and ensuring compliance with regulatory standards for beverage and supplement labeling.

The analysis of water-soluble vitamins is complicated by matrix complexity, metal-analyte interaction, and sensitivity issues. Waters HPLC systems facilitate this through robust methods that enhance reproducibility and accuracy across different platforms, simplifying method transfer and ensuring compliance with regulatory standards for beverage and supplement labeling.

Application Notes

Pomegranate juice

Blog: Recent Trends in Beverage Testing – Vitamins

Today’s food and beverage manufacturers must continually innovate to meet increasing consumer demand for products that support lifestyle and health goals. Read our blog to understand how Waters HPLC and UPLC solutions enable reliable, accurate, and efficient testing methods to ensure that finished beverage products meet manufacturers’ specifications and nutritional label claims.

Today’s food and beverage manufacturers must continually innovate to meet increasing consumer demand for products that support lifestyle and health goals. Read our blog to understand how Waters HPLC and UPLC solutions enable reliable, accurate, and efficient testing methods to ensure that finished beverage products meet manufacturers’ specifications and nutritional label claims.
View Blog
Sports drinks in ice tub

Solutions

With Waters systems, streamline analysis, and accelerate sample throughput tailored to your vitamin testing labs.

With Waters systems, streamline analysis, and accelerate sample throughput tailored to your vitamin testing labs.

See clearly and consistently, with confidence

See clearly and consistently, with confidence
Arc Premier System

Reduce non-specific adsorption from metal interactions in HPLC and UHPLC applications and obtain higher quality, reproducible data with the Arc Premier System.

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing

The next evolution in separation science is here

The next evolution in separation science is here
ACQUITY Premier System

Minimize metal-sensitive analyte loss and improve recovery with the ACQUITY Premier System for ultra-performance liquid chromatography analysis.

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing

Performance that advances your lab

Performance that advances your lab
ACQUITY UPLC H-Class PLUS System

Get the flexibility of quaternary or binary solvent blending and decrease your time to result with the ACQUITY UPLC H-Class PLUS System to improve the characterization of your most complex samples.

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing

The ease of reversed-phase meets the power of normal-phase

The ease of reversed-phase meets the power of normal-phase
ACQUITY UPC2 System

Address routine and complex separation challenges while delivering reliability, robustness, sensitivity, and increased throughput of convergence chromatography techniques with the ACQUITY UPC2 System.

  • Fat-Soluble Vitamin Testing

Highly reliable, low complexity, accurate routine analysis

Highly reliable, low complexity, accurate routine analysis
Arc HPLC System

Replicate and improve the performance of your existing LC vitamin analysis methods without compromising data quality with Arc HPLC System.

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing

A new era of intuitive simplicity

A new era of intuitive simplicity
Alliance iS HPLC System

Reduce human errors, HPLC system downtime, and generate consistent global method performance with the Alliance iS HPLC System to multiply the productivity and efficiency of your QC lab.

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing

Separate beyond question with the power of mass detection

Separate beyond question with the power of mass detection
ACQUITY QDa II Mass Detector

Minimize the risk of unexpected coelutions or components and confirm trace-components with certainty with the ACQUITY QDa II Mass Detector and enhance the analytical value of each analysis.

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing

Waters software streamlines data acquisition, processing, and reporting vitamin testing results.

Waters software streamlines data acquisition, processing, and reporting vitamin testing results.

Simplify data acquisition, processing, and reporting

Simplify data acquisition, processing, and reporting
Empower Chromatography Data System (CDS)

For advanced laboratory data management, including acquisition, processing, and reporting for liquid and gas chromatography instruments, equip your lab with the Empower Chromatography Data System (CDS).

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing

Take control of your laboratory workflow

Take control of your laboratory workflow
NuGenesis Lab Management System (LMS)

Document observations, control procedures, and exchange information with other software solutions with NuGenesis LMS, the analytical electronic laboratory notebook that helps you easily find and collaborate on your results.

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing

Integrated solution to elevate your workflows

Integrated solution to elevate your workflows
Empower Lab Management System (LMS)

From sample submission to data archival, manage your data all from a single, simple dashboard for an integrated approach to your product lifecycle management so you can reduce transcription errors, increase efficiency, and maximize data durability with Empower LMS.

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing

Our reliable and robust columns and consumables can be easily integrated into your beverage testing workflows.

Our reliable and robust columns and consumables can be easily integrated into your beverage testing workflows.

See all of your sample

See all of your sample
MaxPeak Premier Columns

Reduce non-specific adsorption (NSA) of metal sensitive compounds with MaxPeak Premier Columns, the most universal column platform for chromatographers who need to reduce variability risks and save time, all while increasing recovery and sensitivity.

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing

Designed, tested, and guaranteed for routine use

Designed, tested, and guaranteed for routine use
UPLC Columns

Dramatically increase resolution, speed, and sensitivity with Waters Ultra-Performance Liquid Chromatography (UPLC) columns, designed for superior pH stability, maximum retentivity, improved peak shape, and ultimate efficiency.

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing

Create exceptional chromatography and achieve repeatable results

Create exceptional chromatography and achieve repeatable results
HPLC Columns

Resolve your toughest separation challenges with Waters analytical and preparative HPLC columns, which come in 5,800+ column formats, 175+ column configurations, and 21 unique column phases.

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing

Faster, cleaner, and simpler sample preparation starts here

Faster, cleaner, and simpler sample preparation starts here
Sample Preparation Products

Simplify sample preparation with Waters sample preparation solutions for quantitative analysis and deliver samples that are reproducible, yield high recovery, and are free of interferences.

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing

Achieve accurate results for a large variety of beverage product samples using streamlined Waters services.

Achieve accurate results for a large variety of beverage product samples using streamlined Waters services.

A simplified solution for beverage testing application support

A simplified solution for beverage testing application support
Analytical and Laboratory Services

Accelerate your time to results with our on-site application support for beverage testing. Waters ensure a successful solution setup as well as training users through the entire analytical procedure, enabling your laboratory to analyze flavor, additives and preservatives, confidently and seamlessly.

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing

Maximize your financial resources

Maximize your financial resources
Payment Solutions

Take advantage of the most advanced analytical technology available for your laboratory with innovative payment solutions from Waters Capital, and bundle your complete solution in one easy monthly payment.

  • Fat-Soluble Vitamin Testing
  • Water-Soluble Vitamin Testing

The data speaks for itself

The data speaks for itself
Significant improvements in peak shape and sensitivity of vitamin B chromatograms are observed using the ACQUITY Premier LC system
Significant improvements in peak shape and sensitivity of vitamin B chromatograms are observed using the ACQUITY Premier LC system and column with MaxPeak HPS Technology (green traces) compared to the stainless steel setup (red traces). (A) demonstrates these enhancements from the initial injections, while (B) shows the sustained benefits after extensive system use.
Mass detection enables the detection of vitamins at low levels
Mass detection enables the detection of vitamins at low levels, as demonstrated by the SIR chromatogram of vitamin B12 using the ACQUITY QDa Mass Detector (A), compared to the UV chromatogram (B).
The stereoisomers of all-rac-α-tocopheryl acetate were separated into two main peaks
The stereoisomers of all-rac-α-tocopheryl acetate were separated into two main peaks, while RRR-α-tocopheryl acetate showed a single sharp peak within 15 minutes on an ACQUITY UPC² System, offering a reliable method to differentiate between natural and synthetic vitamin E.
Chromatogram for the standard of vitamin A, four isoforms of vitamin E, and two vitamin D, acquired on ACQUITY Arc 2D-LC System
Chromatogram for the standard of vitamin A, four isoforms of vitamin E, and two vitamin D, acquired on ACQUITY Arc 2D-LC System.

Webinars and Resources

Webinar: Rapid Analysis of Vitamins in Fortified Food and Beverages

Webinar: Rapid Analysis of Vitamins in Fortified Food and Beverages
  • Application Notebook

Food and Beverage Quality Control and Compositional Testing

Food and Beverage Quality Control and Compositional Testing
Download
  • Case Study

Manufacturer Reduces Vitamin QC Analysis Times by Up to 90%

Manufacturer Reduces Vitamin QC Analysis Times by Up to 90%
Download
  • Case Study

Improving Standards for Vitamin Analysis using Mass Detection

Improving Standards for Vitamin Analysis using Mass Detection
Download
  • Case Study

Liquid Handling Automation System Streamlines Sample Preparation for Nutritional Analysis

Liquid Handling Automation System Streamlines Sample Preparation for Nutritional Analysis
Download
  • Webinar

Technologies for Reliable Water and Fat-Soluble Vitamins Analysis

Technologies for Reliable Water and Fat-Soluble Vitamins Analysis
Watch

Related

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Learn more about Vitamin Testing Solutions.

Learn more about Vitamin Testing Solutions.
Vitamin c effervescent tablet is dissolving in glass of water
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