Created around Waters proven silica-based, Symmetry® reversed-phase HPLC chemistries, these wide-pore, 300Å columns are well suited for the separation, lab-scale isolation, and HPLC analysis of proteins and other biological compounds.
Designed to provide maximum reproducibility and material recovery of protein and peptide assays, the columns are available in two particle sizes and chemistries:
Particle Sizes | 3.5 µm | 5 µm |
Chemistries | C4 for large peptides and proteins | C18 for smaller peptides |
Pore Size Effects on Resolution – Symmetry 100Å and Symmetry300
Protein: Symmetry300 C4 Versus Competitors
Unmatched Year-to-Year Reproducibility
Improved Peak Shape and Unique Selectivity
· Are the best solution for validation compliance.
Symmetry300 C4 columns have the highest average peak capacity compared to over 20 leading brands of HPLC columns. In the example shown, a difficult protein separation, the Symmetry300 C4 column provided a better separation with better peak shape compared to a leading competitive 300Å column.
Protein: Symmetry300 C4 Versus Competitors
Waters cartridge system requires re-usable endfittings, which you order when purchasing a Waters HPLC cartridge column for the first time. Connect these cartridge columns to your HPLC instrument using Waters standard connectors.
Cartridge End-Fittings
3.0 x 20 mm, 3.9 x 20 mm use Part Number WAT046905
Universal Guard Holder (Use on any column)