Purification Solutions

Waters’ comprehensive and flexible portfolio provides a wide range of scale and throughput capabilities. Whether requiring single sample or high-throughput purification, Waters has the proven solutions to meet a laboratory’s purification requirements.

From semi-automated modular systems to fully automated mass-directed systems, Waters’ solutions are fully adaptable.

Prep 150 LC System

• A simple solution ideal for simple purification needs
• Quickly process any sample for high purity and recovery

AutoPurification LC Prep System

• Sophisticated solution for complex purification needs
• Maximize productivity with mass-directed purification to efficiently target the compound of interest
• Automate the purification process to accelerate production of drug candidates
• Easily integrate mass-directed purification

Watch: AutoPurification System Animation

Waters’ scalable, environmentally friendly systems satisfy the most challenging purification needs while minimizing costs.

Prep 15 SFC Purification System

• Automated sample handling accommodates both sample injection and fraction collection within a single, open-bed format
• Improve detection sensitivity and peak tracking while interpreting and comparing complex data
• Versatile configurations to meet any need

Prep 150 AP SFC System

• Leverage automated sample handling, column switching, fraction collection and tracking for fast separations, high resolution, and high throughput
• Support a robust, efficient and cost-effective open access environment in any purification lab
• Gain superior fraction recovery rates for reduced solvent evaporation time and processing costs

Prep 150 Mgm SFC System

• Ideally designed for high-throughput, semi-prep to preparative scale purifications made for repeat injection
• Easily operate at higher flow rates than traditional HPLC without significant increase in back pressure
• High speed SFC purification and improved resolution of compounds for higher purity isolations

Prep 350 SFC System

• For large scale purification: from 100g to kilogram scale
• Ideally suited for large compound campaigns
• Modified stream injection improves sample loading without peak distortion caused by strong solvent effects
• Stacked injection capability improves isocratic purification productivity

For chemists who are working with UV-triggered purification, knowing the identity of the fractions is absolutely important to determine which fractions to carry on to the next steps. Although LC-MS provides mass spectral information for identity, it requires long methods and potentially higher costs. RADIAN ASAP provides chemists with easy access to mass spectral data for near instantaneous assessment of identity of purification fractions, increasing laboratory efficiency.
 

Waters’ Informatics solutions provide a powerful suite of solutions for instrument control, scientific data management, network integration, and compliance management:

• Maximize daily laboratory operations with OpenLynx Open Access software and efficiently manage data with Nugenesis Lab Management System
• Waters’ FractionLynx Application Manager, coupled with OpenLynx, manages and automates the purification process with walk-up access, allowing labs to easily perform purifications
• ChromScope Software for use on Waters purification systems enables fully automated instrument control, development of methods, and purification of samples. Effortless integration with the ACQUITY QDa Detector is now possible, providing analytical confidence from the selectivity that mass detection brings to analysis

Waters’ FlexCHOICE: mySystem Coverage helps ensure high laboratory productivity and uptime, along with top system peak performance, all while considering a lab’s budget realities.

To help you cost-effectively adopt the latest separations and mass spec technology, the FlexUP Technology Renewal Program helps you modernize your lab, improve data quality, and lower your total cost of ownership. FlexCAPITAL Lab Solutions offers an all-inclusive monthly payment plan with no capital outlay, eliminating unanticipated maintenance expenses and reducing downtime with state-of-the-art instrumentation.