Mass Spectrometry (MS) Upgrades

Mass Spectrometry (MS) Upgrades

Improve your instrument's serviceability and extend its lifetime with Waters MS instrument hardware upgrades, conversion kits, and accessories based on the latest technologies.

Improve your instrument's serviceability and extend its lifetime with Waters MS instrument hardware upgrades, conversion kits, and accessories based on the latest technologies.
Waters lab with UPLC Systems and scientists working

Mass Spectrometry (MS) Upgrades

Mass Spectrometry (MS) Upgrades

Waters offers a range of MS hardware upgrades and sample inlet options that will improve your system's control and data acquisition functions, increase its analytical capabilities, and extend its operational lifetime.


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Increase the analytical capabilities and productivity of your APGC enabled Waters mass spectrometer by converting to APGC v2.0.

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The Atmospheric Solids Analysis Probe is a useful tool for the rapid direct analysis of volatile and semi-volatile solid and liquid samples using atmospheric pressure ionisation.

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The Atmospheric Pressure GC (APGC) source field upgrade allows laboratories to extend the capabilities of their LC-MS analytical instrumentation, by incorporating the ability to perform AP GC-MS on a single MS platform.

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Provides a clean, dry, and lubricant-free vacuum and environmentally superior alternative to the standard oil-sealed rotary vacuum pump.

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When analyzing post-translational modifications and top-down sequencing of Biomolecules are all important, Electron Transfer Dissociation (ETD) provides a unique solution.

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The ionKey UPLC microflow source provides high sensitivity, quantitative, sample-limited analyses through direct non-split operation via an easy to use iKey separations device.

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APCI is an effective method for analyzing lower-polarity compounds. The high-efficiency IonSABRE APCI probe offers significant improvements in sensitivity compared with earlier versions of probe, particularly at higher liquid flow rates.

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The LockSpray dual electrospray ion source optimizes the co-introduction of analyte and lock mass compound directly into the ion source, providing authenticated exact mass measurement in MS and MS/MS modes.

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The NanoLockSpray dual electrospray ion source accessory with optimized co-introduction of analyte and lock mass compounds provides authenticated exact mass measurement in NanoFlow LC-MS and LC-MS/MS modes of operation.

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SYNAPT G2 MS/HDMS series instruments upgraded with a MALDI source system provide the uncompromised exact mass characterization of compounds using MALDI-MS, MALDI-MS/MS, and MALDI-MS/IMS/MS (HDMS only) analyses.

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Upgrade your SYNAPT MS series instrument to full HDMS capability to benefit from high efficiency ion mobility separations.

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Replace your existing laser 200 Hz or 1 KHz laser with a 2.5 KHz high repetition rate solid state laser system, offering a smaller spot size (avg 60 µm) and reduced ablation times for MALDI Imaging experiments.
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Mass Spectrometry (MS) Upgrades: Enhance Performance and Extend Lifespan

Upgrading mass spectrometry (MS) instruments helps laboratories improve accuracy, efficiency, and reliability while extending equipment lifespan. Over time, MS systems can experience wear, leading to reduced performance and higher maintenance costs. Hardware upgrades, such as improved ion sources, detectors, and vacuum systems, enhance sensitivity, stability, and data quality.

Software upgrades also play a crucial role by improving data analysis, automation, and regulatory compliance. Advanced processing tools allow for faster, more accurate interpretation of results while streamlining workflows and reducing manual labor. Keeping software up to date ensures adherence to industry standards and enhances overall efficiency.

Additionally, conversion kits and accessories provide greater flexibility, allowing laboratories to switch between ionization techniques, improve system interfaces, and enhance sample handling. These upgrades help labs adapt to evolving research needs without requiring a full instrument replacement.

Waters offers a range of MS upgrades tailored to optimize instrument performance and reliability. Whether upgrading hardware, software, or accessories, these enhancements help laboratories achieve higher precision, efficiency, and cost savings. Investing in MS upgrades ensures laboratories stay competitive in scientific research and industry applications.