HPLC Columns

State-of-the-art Reversed-Phase and HILIC HPLC Columns

Waters offers a wide range of analytical and preparative chromatography columns to meet the needs of virtually every application. The Waters Column Advisor recommends the most appropriate column depending on the on the application requirements you need to consider and the column characteristics you are looking for. Separations developed on our analytical columns can be directly scaled up to preparative columns. We supply a wide range of phase chemistries in numerous column dimensions for preparative work to meet your scale-up needs. All chromatography columns meet stringent specifications to ensure excellent performance and column-to-column reproducibility. We also offer a wide range of accessoriesto support these columns.


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CORTECS Columns Maximize resolution and peak capacity for LC separations with CORTECS solid-core columns in 1.6 and 2.7 µm across 7 column chemistries.
XBridge Columns Experience XBridge HPLC and UHPLC Columns, ideal for methods development at extreme temperatures and mobile-phase pH. Explore XBridge BEH Column chemistries today.
XSelect Columns Get superior selectivity and peak shape for basic compounds with XSelect HPLC and UHPLC Columns. Discover our CSH and high-strength silica columns. Visit today.
VanGuard Column Protection Safeguard analytical HPLC, UHPLC, and UPLC columns from the effects of damaging particulates and chemical contaminates with VanGuard Cartridges and Pre-columns.
UHPLC Columns Our focused selection of UHPLC columns highlight the performance advantages modern UHPLC instrumentation.
Symmetry HPLC Columns Get predictable analytical performance and ensure batch-to-batch reproducibility with high purity silica-based Symmetry HPLC Columns.
Bioseparations Columns & Consumables Chemistry consumables for the accurate analysis of peptides, proteins, oligonucleotides, glycans, and amino acids.
Atlantis HPLC Columns Improve chromatographic performance, retention, and stability for polar compounds with Atlantis HPLC Columns. Discover Atlantis C18 and HILIC column chemistries now.
SunFire Columns Get exceptionally high mass loading for both analytical and preparative columns with SunFire HPLC Columns. Discover SunFire Silica, C8, and C18 columns.
XTerra Columns Perform low and high pH drug discovery, method development and purification separations with XTerra hybrid particle technology HPLC columns. Learn more.
Nova-Pak Columns Get higher resolution and efficiency for HPLC with Nova-Pak analytical and semi-preparative columns. Discover Nova-Pak C18, C8, Cyano & Phenyl column chemistries.
Waters Spherisorb HPLC Columns Discover unique separation selectivities with Waters Spherisorb Columns, the most widely referenced products for analytical and preparative column chromatography.
Resolve Columns Achieve high retention and high resolution of polar compounds with non-endcapped Resolve Columns available in C18, C8 and Cyano column chemistries
µBondapak and Bondapak Columns Separate acidic, basic, and neutral compounds with µBondaPak and BondaPak Columns. These HPLC columns are available in phenyl, C18, cyano and NH2 column chemistries.
µPorasil/Porasil Columns Get reliable normal-phase chromatography separations with non-bonded, silica-based μPorasil and Porasil Columns. Research µPorasil/Porasil HPLC Column options.
Waters PAH Columns Get superior peak identification and quantitation for Polyaromatic Hydrocarbons (PAHs) compounds with Waters PAH C18 HPLC Columns.
Protein-Pak Columns Achieve high-quality LC-based analyses & lab scale purifications of peptides and proteins with Protein-Pak IEX & HIC Columns, designed for use on HPLC and UPLC systems.
Shodex RSpak Columns Polymeric reversed-phase columns for basic compounds and applications requiring a broad pH range (2–12). Shodex RSpak Columns chemistries include DE-613 and DS-613.
Column Accessories Waters offers a variety of tubings, fittings, column connections, and replacement parts for columns and cartridges.

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