An inclusive solution (columns, standards, and mobile-phase concentrates) for characterizing, monitoring, and quality control testing charge variants of mAb-based therapeutics from discovery and development through manufacturing. Scientists can easily obtain desired data using defined methods on any LC platform without sacrificing performance. The benefits include:
Flexible, Reproducible, High-Resolution SeparationsCharge variant analysis for monoclonal antibodies and other proteins is a critical quality attribute to understand. This product portfolio offers a solution-based platform for LC and LC-MS users utilizing robust salt and pH gradient methods. |
Next Generation IEX Column TechnologyThe BioResolve SCX mAb Columns are based on non-porous, 3 μm particle for optimal protein diffusion kinetics and pressure tolerance for use on HPLC, UHPLC, and UPLC systems.
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Increased Lifetime Without Sacrificing PerformanceGuard columns are commonly used to prevent the unintended injection of sample of eluent particles that could adversely impact column lifetime. The VanGuard FIT (Fully Integrated Technology) is integrated into the column, providing ease-of-use without sacrificing performance, and ensuring maximum column lifetime. |
BioResolve CX pH Buffer ConcentratesDesigned alongside the BioResolve SCX mAb Columns, these buffer concentrates are:
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IonHance CX-MS pH Buffer ConcentratesDeveloped for use with the BioResolve SCX mAb, 3 μm Columns, and designed to deliver robust, charge-based separations and high-quality, MS-spectral data.
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Batch and Column ConsistencyThese guards and columns are batch tested using Waters, NIST-based, mAb Charge Variant Standard to help benchmark column and system performance. |
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