• Application Note

Atorvastatin - XTerra RP18 

Atorvastatin - XTerra RP18 
  • Waters Corporation
Download PDF Download PDF
Atorvastatin cholesterol lowering drug chemical structure

This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief demonstrates the analysis of atrovastatin using XTerra RP18 Columns. 

Introduction

In this study the compound analyzed is atorvastatin. 

Atorvastatin

Experimental

Conditions

Column:

XTerra RP18 4.6 x 100 mm, 3.5 µm

Part number:

186000438

Mobile phase A:

10 mM NH4COOH, pH 3.0

Mobile phase A:

10 mM NH4HCO3, pH 7.0

Mobile phase A:

10 mM NH4HCO3, pH 10.0

Mobile phase B:

ACN

Isocratic Conditions as Indicated

Flow rate:

1.4 mL/min

Injection volume:

2 µL

Sample Concentration:

0.25 mg/mL

Temperature:

30 °C

Detection:

UV @ 254 nm

Instrument:

Alliance 2795 HT, 2996 PDA

Mobile Phase pH

USP Tailing

3.0

1.04

7.0

1.19

10.0

1.11

Results and Discussion

Atorvastatin

Featured Products

WA20738.014, June 2002

Back To Top Back To Top