ProteinWorks eXpress Digest Kit - Ambient Refill Kit
Bioanalytical laboratories look for lab equipment that give them a competitive edge as the therapeutic and research landscape shifts from small molecule to large molecule analysis.
ProteinWorksTM Sample Preparation Kits enable Discovery and Early Development laboratories to obtain consistent, reproducible, and sensitive protein quantification using the surrogate peptide method, in conjunction with strong and dependable LC-MS methodologies and equipment. ProteinWorks offers eXpress Digest Kits for quick, repeatable protein digestion, a mAb system check and training standard, and an Elution SPE kit for post-digestion cleanup. ProteinWorks is unequaled in performance and adaptability.
The Waters® ProteinWorksTM eXpress Digest Kits are versatile, widely applicable sample preparation lab equipment that includes pre-measured, lot traceable reagents that are optimized for accurate, precise, and reliable LC-MS protein quantification using the surrogate peptide technique.
Due to their complex, multi-segment structure, protein quantification workflows are subject to substantial variability. In order to produce reliable, reproducible results for important research decisions, assays must adhere to approved accuracy and precision standards. To enable you to achieve single-digit intra-kit and inter-kit repeatability across a number of monoclonal antibodies, ProteinWorks eXpress Digest Kits provide a simplified, kit-based methodology.
It can be difficult to achieve sensitivity, repeatability, standardization, and accuracy while maintaining enough flexibility to support various LC-MS protein quantification procedures. ProteinWorks is optimized for a range of different processes, giving it ample flexibility to produce the best results for your assay needs and the analyte of interest without the limitations of competitive kit-based techniques.
Assay sensitivity is influenced by choices of the chemicals used, their concentrations, time, temperature, and the number of steps. Getting the desired detection limits can be difficult. With pre-weighed, lot-traceable reagents and straightforward, step-by-step instructions, ProteinWorks' universal kit-based sample preparation approach enables quick quantification of infliximab down to 10 ng/mL.
You may also want to explore the ProteinWorks µElution SPE Clean-up Kit. This kit comes with an improved SPE methodology with Oasis uElution technology that delivers maximal peptide recovery and eliminates matrix interferences such as digest reagents.
