ACQUITY Premier Oligonucleotide C18 Column 130Å 186009486 angle right

SKU: 186009903
XBridge Premier Oligonucleotide BEH C18 Column, 130Å, 2.5 µm, 4.6 mm X 150 mm, 1/pk

XBridge Premier Oligonucleotide BEH C18 Column | 186009903


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Product Description

XBridge Premier Oligonucleotide Columns are used to separate detritylated synthetic oligonucleotides based on ion-pair, reversed-phase chromatography. Each column is QC tested using Waters MassPrep OST standards to ensure repeatable performance for your most demanding oligonucleotide assays. This column is part of the MaxPeak Premier Class of Columns, which deliver the chromatographic performance expected from our particle technologies while increasing reproducibility, peak shape, and recovery for metal-sensitive analytes.

Specifications

  • Chemistry

    C18

  • Separation Mode

    Reversed Phase

  • Particle Substrate

    Hybrid

  • pH Range Min

    1 pH

  • pH Range Max

    12 pH

  • Maximum Pressure

    10000 psi (690 Bar)

  • Endcapped

    Yes

  • Silanol Activity

    Low

  • Particle Shape

    Spherical

  • Particle Size

    2.5 µm

  • Endfitting Type

    Parker-style

  • Pore Size

    130 Å

  • Format

    Premier Column

  • Surface Area

    185

  • System

    UHPLC, UPLC

  • Particle Technology

    BEH

  • Technique

    LC

  • USP Classification

    L1

  • Inner Diameter

    4.6 mm

  • Length

    150 mm

  • Carbon Load

    18 %

  • eCord

    Yes

  • UNSPSC

    41115711

  • Application

    Oligonucleotide, Gene Therapeutics

  • Brand

    XBridge

  • Product Type

    Columns

  • Units per Package

    1 pk

Product Support

Documents

Documents



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XBridge Premier Oligonucleotide BEH C18 Column, 130Å, 2.5 µm, 4.6 mm X 150 mm, 1/pk

Using reverse-phase, ion-pair chromatography systems to perform LC analysis of oligonucleotides can present a series of considerations that scientists must work hard to overcome. But with the XBridge Premier Oligonucleotide BEH C18 Column, those considerations are much easier to satisfy. Characterized by its ability to purify and analyze heterogeneous entities, including DNA and RNA species, this hybrid column offers increased mechanical stability and repeatable performance when its needed most. And because scalability is of the utmost importance, the XBridge Premier Oligonucleotide BEH C18 Column provides seamless method transfer capabilities. Tell your lab manager today about XBridge Premier technology, or add one of these desirable columns to your toolkit today.

For increased confidence in results, Waters scientists went back to the lab to develop a chromatography consumable that prioritizes mechanical and chemical stability over all. Because of this, the XBridge Premier Oligonucleotide BEH C18 Column was produced. Oligonucleotide analysis offers many unique challenges that even the most knowledgeable scientist must work hard to overcome, and MaxPeak High Performance Surface technology incorporated into this analytical column makes those challenges easy to overcome. How?
The nature of oligonucleotide analysis makes non-specific adsorption a major consideration, but the XBridge Premier Oligonucleotide BEH C18 Column is equipped to handle all that with ease.

Another factor to consider during oligonucleotide analysis is the particulate or chemical fouling of your analytical column over time. To curb that obstacle, Waters scientists are proud to present VanGuard FIT technology. This column protection tech seamlessly integrates onto your analytical column and into your workflow to provide enhanced protection from many of the factors that can harm peak signal intensity. Buy an XBridge Premier BEH C18 Column VanGuard FIT Cartridge to gain this enhanced protection.

Not performing oligonucleotide analysis?
Thanks to the wide variety of base particles and column chemistries offered by the XBridge Premier Column family, you’re sure to find the right chromatography consumable when you consider XBridge Premier. But finding the right separation tool is only one thing to consider before heading into the lab. When you need quality control reference materials, lab informatics, elution plates, glass vials or other lab essentials, we have exactly what you need at Waters. Simply shop for lab equipment to enjoy the quality and performance offered by Waters products.

What is the XBridge Premier Oligonucleotide BEH C18 Column Best Used For?

The XBridge Premier Oligonucleotide BEH C18 Column is uniquely suited for DNA and RNA oligonucleotide separations.