ACQUITY PREMIER Peptide CSH C18 Column 130Å 186009488 angle right

SKU: 186009837
XBridge Premier Oligonucleotide BEH C18 Column, 130Å, 2.5 µm, 2.1 x 100 mm

XBridge Premier Oligonucleotide BEH C18 Column | 186009837


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Product Description

XBridge Premier Oligonucleotide Columns are used to separate detritylated synthetic oligonucleotides based on ion-pair, reversed-phase chromatography. Each column is QC tested using Waters MassPrep OST standards to ensure repeatable performance for your most demanding oligonucleotide assays. This column is part of the MaxPeak Premier Class of Columns, which deliver the chromatographic performance expected from our particle technologies while increasing reproducibility, peak shape, and recovery for metal-sensitive analytes.

Specifications

  • Chemistry

    C18

  • Separation Mode

    Reversed Phase

  • Particle Substrate

    Hybrid

  • pH Range Min

    1 pH

  • pH Range Max

    12 pH

  • Maximum Pressure

    18000 psi (1240 Bar)

  • Endcapped

    Yes

  • Silanol Activity

    Low

  • Particle Shape

    Spherical

  • Particle Size

    2.5 µm

  • Endfitting Type

    Parker-style

  • Pore Size

    130 Å

  • Format

    Premier Column

  • Surface Area

    185

  • System

    UHPLC, UPLC

  • Particle Technology

    BEH

  • Technique

    LC

  • USP Classification

    L1

  • Inner Diameter

    2.1 mm

  • Length

    100 mm

  • Carbon Load

    18 %

  • eCord

    Yes

  • UNSPSC

    41115709

  • Application

    Oligonucleotide, Gene Therapeutics

  • Brand

    XBridge

  • Product Type

    Columns

  • Units per Package

    1 pk

Product Support

Documents

Documents



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XBridge Premier Oligonucleotide BEH C18 Column, 130Å, 2.5 µm, 2.1 x 100 mm

Performing reverse-phase separations of synthetic oligonucleotides requires a tool that’s up for conquering various challenges, and the XBridge Premier Oligonucleotide BEH C18 Column is that tool. Tested with Waters OST standards to ensure repeatable performance even under the most demanding conditions. Plus, every XBridge Premier Column has earned the MaxPeak designation, which is only given to chromatography consumables that incorporate technology to prevent unwanted analyte-surface interactions from occurring. That kind of protection is incredibly important when you’re in the lab. Add the XBridge Premier Oligonucleotide BEH C18 Column to your lab’s toolkit today, or tell your lab manager now that you want XBridge Premier performance at your command.

The XBridge Premier Oligonucleotide BEH C18 Column is uniquely suited to separate detritylated synthetic oligonucleotides based on ion-pair, reverse-phase chromatography. Not only does this make it a top choice for scientists working with oligonucleotides, this hybrid column reduces column passivation and conditioning, making way for a more efficient workflow. And thanks to the Ethylene-Bridged Hybrid (BEH) particle used, incredible stability is prioritized. This especially comes in handy with difficult oligonucleotide separations. Want to further protect your analytical column?
Shop VanGuard FIT Cartridges.

Mechanical strength and chemical stability are two hugely important facets of the XBridge Premier Oligonucleotide BEH C18 Column. Waters scientists heard the calls from their peers to create a product designed specifically for oligo separations, but they didn’t stop when those calls were answered. Instead, they continued to innovate and incorporate more desirable features into this column, like its ability to better control silanol activity. This all adds up to an essential tool you won’t want to be without.

What’s MaxPeak High-Performance Surface Technology?
Even the most knowledgeable scientists have to overcome the common concern of unwanted analyte-surface interactions during mobile phases. That’s where MaxPeak comes into consideration. Implemented through a special coating within your analytical column, MaxPeak reduces the risk for those interactions. What’s more, MaxPeak is included in every XBridge Premier Column available. And with plenty of column chemistries and specific separation features to choose from, you’re sure to find the right match when you shop XBridge Columns.

Oligonucleotide separation equipment, lab informatics, quality control reference materials; you’ll find these items and so many more at Waters. Shop for lab equipment now to check off the boxes on your lab’s procurement list.

What is the XBridge Premier Oligonucleotide BEH C18 Column’s pH Range?

The XBridge Premier Oligonucleotide BEH C18 Column offers a pH range of 1-to-12 pH.