BioResolve RP mAb Polyphenyl Method Validation Kit, 450Å, 2.7 µm, 1 mm X 150 mm, 3/pk

To establish the identity and purity of mAb-based biotherapeutic drugs, method development and validation must run smoothly. But when you’re using one chromatography column to validate methods, you might not have the flexibility and speed needed to rapidly reproduce separations and move forward in your analytical workflow. To help, we’re happy to provide the BioResolve RP mAb Polyphenyl Method Validation Kit. This solutions kit includes three BioResolve RP mAb Polyphenyl Columns packed with the same sorbent but from three different batches. Using three different batches of sorbent helps to instill confidence in the scientists using these columns to perform reversed-phase analysis of IgG monoclonal antibodies and their fragments. Plus, because upholding peak system performance is of the utmost importance, we’ve included three vials each of the Intact mAb Mass Check Standard and mAb Subunit Standard. Take your mAb and biotherapeutic drug analyses to the next level and easily conquer analytical challenges with the BioResolve RP mAb Polyphenyl Method Validation Kit.

To properly harness the selectivity and resolution provided by the BioResolve RP mAb Polyphenyl Column, the rugged superficially porous silica particles within the column are functionalized using a novel polyphenyl bonding process. This high-coverage bonding process paired with the solid-core column technology provides better resolution at higher flow rates. Plus, speaking of higher flow rates, you can use the BioResolve RP mAb Polyphenyl Column on all UPLC, UHPLC and HPLC systems. That kind of flexibility is greatly needed during method development and we’re happy to provide a chromatography column that can handle different LC systems with remarkable ease.

In addition to offering an innovative solution for intact protein analysis of mAbs and antibody drug conjugates, the BioResolve RP mAb Polyphenyl Column also offers a wide and usable pH range to accommodate varying analytes. And if you’re curious about how this column withstands higher backpressures, you can rest easy knowing this column is more than capable.

Want to protect your columns from contamination and increase column lifetimes in the process?
With the BioResolve RP mAb Polyphenyl VanGuard Cartridge, you can do that and so much more. This state-of-the-art column protection solution integrates seamlessly into your existing analytical workflow to provide enhanced protection from contaminants that may be lingering in the mobile phase stream. Please note that this cartridge is no replacement for following proper sample preparation protocols.

Once you’ve added the BioResolve RP mAb Polyphenyl Method Validation Kit to your cart, make sure to shop lab equipment to explore all of our other incredible products and resources. It’s our passion to help your lab be more efficient and profitable with our products. See how Waters can help your own goals today.