Line drawing of a column

SKU: 186009018
BioResolve RP mAb Polyphenyl Method Validation Kit, 450Å, 2.7 µm, 1 mm X 100 mm, 3/pk

BioResolve RP mAb Polyphenyl Method Validation Kit | 1 x 100mm | 186009018


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Product Description

The first choice for reverse phase protein separation and analysis, BioResolve RP mAb Polyphenyl Method Validation Kit, 450Å, 2.7 µm, 1 mm X 100 mm Columns contain 2.7 µm superficially-porous-silica particles having an average pore diameter of 450Å. The particles are functionalized with a proprietary polyphenyl bonding process that was specifically designed for LC or LC-MS analyses of intact IgG monoclonal antibodies and their fragments. Each batch is qualified using a gradient separation of the Waters mAb Subunit Standard (p/n: 186008927). This Method Validation Kit (MVK) Part Number contains (3) (p/n: 186009016) columns from (3) different manufactured batches.

Suggested Use: Intact protein and mAb subunit analysis, Protein Analysis, ADC characterization, AAV, Antibody Conjugates

Specifications

  • Separation Mode

    Reversed Phase

  • Temperature Limits

    90 C

  • Maximum Pressure

    10000 psi (689 Bar)

  • Particle Size

    2.7 µm

  • Pore Size

    450 Å

  • QC Tested

    Protein

  • System

    HPLC, UHPLC, UPLC

  • USP Classification

    L11

  • UNSPSC

    41115709

  • Brand

    BioResolve

  • Product Type

    Column Kits

  • Units per Package

    3 pk

Product Support

Documents

Documents



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BioResolve RP mAb Polyphenyl Method Validation Kit, 450Å, 2.7 µm, 2.1 mm X 150 mm, 3/pk

Scientists across the world are using reverse-phase chromatography techniques to better understand biotherapeutic drugs being distributed, which means scientists also need the chromatography column that can achieve successful mAb analysis despite a few challenges along the way. That’s why we’re happy to present the BioResolve RP mAb Polyphenyl Method Validation Kit, which gives method development scientists everything they need to develop and validate their chosen method. Each kit comes with three BioResolve RP mAb Polyphenyl Columns for your precious separations and three vials each of the Intact mAb Mass Check Standard and mAb Subunit Standard for LC-MS system and instrument performance verification purposes. What’s more, the BioResolve RP mAb Polyphenyl Columns can be equipped with VanGuard column protection technology to prevent contaminants from causing variations in your data. Learn more about the BioResolve RP mAb Polyphenyl Method Validation Kit, then tell your lab manager to add one to your lab’s procurement list today.

The BioResolve RP mAb Polyphenyl Column offers rugged silica particles that are functionalized by a novel polyphenyl bonding process that makes this column incredibly stable, even at low pH. The polyphenyl bonding process is also high coverage, which means it actively prevents carryover effects from occurring as you continue with method development. And because method transfer is always of the utmost importance, we’re eager to report that the BioResolve RP mAb Polyphenyl Column can be used on all UHPLC, UPLC and HPLC systems. This kind of flexibility is greatly appreciated, as method development scientists need to be able to move quickly and efficiently to verify data.

Protecting your BioResolve RP mAb Polyphenyl Columns from contamination is a top priority when you need to rapidly reproduce separations. To help with that, we’re happy to provide the BioResolve RP mAb Polyphenyl VanGuard Cartridge. This cartridge offers the same workable pH range and inner diameter as the accompanying column to provide a chemically and mechanically secure column protection solution. Add it to your workflow now and you’ll experience improved overall column lifetimes.

We have much more than just mAb analysis solutions at Waters, as we also offer a vast array of chromatography consumables, solution kits, lab informatics, quality control reference materials and so much more. You need only shop lab equipment to discover everything we have to offer.

What’s the Average Pore Diameter of the BioResolve RP mAb Polyphenyl Column?

The average pore diameter of the BioResolve RP mAb Polyphenyl Column is 450Å.