Waters Oligonucleotide Separation Technology columns are based on the second generation of hybrid-silica BEH Technology particles functionalized with C18. The separation of detritylated synthetic oligonucleotide samples is based on the well-established method of ion-pair, reversed-phase chromatography. The availability of 1.7µm UPLC technology or 2.5µm HPLC particles in various column dimensions provides flexibility to meet various laboratory-scale isolation or analysis needs and delivers exceptional sample resolution and superior column life. In addition, Waters manufacturing and quality control testing procedures help ensure consistent batch-to-batch and column-to-column performance regardless of application demands.
Chemistry |
C18 |
Particle Size |
2.5 µm |
Pore Size |
130 Å |
Format |
OBD Prep Column |
Inner Diameter |
19 mm |
Length |
50 mm |
UNSPSC |
41115854 |
Application |
Oligonucleotide, Gene Therapeutics |
Brand |
XBridge |
Product Type |
Columns |
Units per Package |
1 pk |
XBridge Oligonucleotide BEH C18 OBD Prep Column, 130Å, 2.5 µm, 19 mm X 50 mm, 1/pk
Leverage the flexibility to meet various laboratory-scale isolation or analysis needs and achieve exceptional sample resolution and superior column life using the XBridge Oligonucleotide BEH C18 OBD Prep Column. Waters Oligonucleotide Separation Technology columns are based on the second generation of hybrid-silica BEH Technology particles functionalized with C18. The lab equipment conducts separation of detritylated synthetic oligonucleotide samples based on the well-established method of ion-pair, reversed-phase chromatography. In addition, Waters' manufacturing and quality control testing procedures help ensure consistent batch-to-batch and column-to-column performance regardless of application demands.
Use the XBridge Oligonucleotide BEH C18 OBD Prep Column to benefit from its exceptional resistance to mechanical chromatographic bed failure by leveraging the OBD design that is resistant to poor solubility and pressure shocks associated with large volumes of pure organic solvent. As the column also offers consistent column-to-column performance, you can easily reduce the lab equipment costs through extended lifetimes and minimized equipment replacement. This is made possible by adhering to the strictest manufacturing conditions such as the cGMP, ISO 9001:2000 using ultra-pure reagents.
Achieve lab-scale separations for greater throughput in a faster, more efficient manner with the XBridge Oligonucleotide BEH C18 OBD Prep Column. It also has the ability to directly scale from UPLC or HPLC screening to lab-scale purification. In addition to this, the Waters patented OBD preparative column design and packing process enables you to get predictable, uniform density profiles throughout the column. There is no potential for voids because during the capping process, there is no overcompression or disruption in any non-uniform way.
The Optimum Bed Density (OBD) design used in the XBridge Oligonucleotide BEH C18 OBD Prep Column is specially formulated to exhibit integrity and stability required in a preparative column used in rapid, high-purity, compound isolations.
Use our website and catalog to find varieties of this product with different specifications, and explore more information on our product offerings and available technology. You can also learn ways to contact our various offices for assistance through the catalog and website as well as shop for lab equipment.
You may also want to explore the XBridge Oligonucleotide BEH C18 Column, 130Å, 2.5 µm, 4.6 mm X 50 mm, 1/pk.
Is Oligonucleotide A Protein?
Oligonucleotides are short, single- or double-stranded DNA or RNA molecules. They include antisense oligonucleotides (ASO), RNA interference (RNAi), and aptamer RNAs.