BioResolve RP mAb Polyphenyl Method Validation Kit, 450Å, 2.7 µm, 3 mm X 150 mm, 3/pk

Classic reversed-phase monoclonal antibody analysis requires a column that can easily withstand analytical challenges as you move forward in your workflow. And with the BioResolve RP mAb Polyphenyl Method Validation Kit, you’ll have everything you need to enhance your workflow for mAb separations and analyses. This all-in-one solution kit includes three BioResolve RP mAb Polyphenyl Columns for your separations, and they’ve all been outfitted with the same sorbent from three separate batches. This way you can be sure of the performance and selectivity across all three columns. Plus, this kit comes with three vials each of the Intact mAb Mass Check Standard and mAb Subunit Standard for performance verification purposes. The BioResolve RP mAb Polyphenyl Method Validation Kit is here to transform the way you approach monoclonal antibody separations and antibody drug conjugate analyses. Ask your lab manager to add one to your procurement list or simply purchase and have one shipped directly to you today.

How do the BioResolve RP mAb Polyphenyl Columns perform?
Well, for one, they’re designed specifically to provide a reversed-phase solution for intact and IdeS digested monoclonal antibodies. But how it’s designed to do that is much more interesting. At the heart of each BioResolve RP mAb Polyphenyl Column, there’s a group of superficially porous silica particles that are functionalized by a novel polyphenyl bonding process that was specifically designed for the LC-MS or LC analysis of intact IgG monoclonal antibodies and their fragments. What’s more, the high-coverage bonding prevents carryover effects and improves low pH stability in the process.

Properly validating methods in monoclonal antibody and antibody drug conjugate analysis is easy with the BioResolve RP mAb Polyphenyl Method Validation Kit, as each included column can be used on all UHPLC, UPLC and HPLC systems. When method transfer is part of your analytical workflow, you’ll find that these columns exhibit the kind of flexibility you want for such a procedure. Plus, thanks to the combination of phenyl bonding and solid-core technology, you can maximize the resolving power and selectivity of various analyzed protein samples with ease.

At Waters, we have the products, equipment and resources to take your laboratory to the next level. From solution kits and quality control reference materials to full LC-MS systems and classic chromatography consumables, we truly have it all. Shop lab equipment to explore all of the incredible products and resources available at Waters.