Line drawing of a column

SKU: 186008958
BioResolve RP mAb Polyphenyl Method Validation Kit, 450Å, 2.7 µm, 3 mm X 100 mm, 3/pk

BioResolve RP mAb Polyphenyl Method Validation Kit | 3 x 100mm | 186008958


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Product Description

The first choice for reverse phase protein separation and analysis, BioResolve RP mAb Polyphenyl Method Validation Kit, 450Å, 2.7 µm, 3 mm X 100 mm Columns contain 2.7 µm superficially-porous-silica particles having an average pore diameter of 450Å. The particles are functionalized with a proprietary polyphenyl bonding process that was specifically designed for LC or LC-MS analyses of intact IgG monoclonal antibodies and their fragments. Each batch is qualified using a gradient separation of the Waters mAb Subunit Standard (p/n: 186008927).

This Method Validation Kit (MVK) Part Number contains (3) (p/n: 186008949) columns from (3) different manufactured batches.

Note: p/n: 176004165 includes the (3) (p/n: 186008949) columns from (3) different manufactured batches plus three vials of the Intact mAb Mass Check Standard (p/n: 186006552) and three vials of the mAb Subunit Standard (p/n: 186008927).

Suggested Use: Intact protein and mAb subunit analysis, Protein Analysis, ADC characterization, AAV, Antibody Conjugates

Specifications

  • Separation Mode

    Reversed Phase

  • Temperature Limits

    90 C

  • Maximum Pressure

    10000 psi (689 Bar)

  • Particle Size

    2.7 µm

  • Pore Size

    450 Å

  • QC Tested

    Protein

  • System

    HPLC, UHPLC, UPLC

  • USP Classification

    L11

  • UNSPSC

    41115709

  • Brand

    BioResolve

  • Product Type

    Column Kits

  • Units per Package

    3 pk

Product Support

Documents

Documents



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BioResolve RP mAb Polyphenyl Method Validation Kit, 450Å, 2.7 µm, 3 mm X 100 mm, 3/pk

If method development for the separation of monoclonal antibodies in reverse-phase chromatography is your goal, then the BioResolve RP mAb Polyphenyl Method Validation Kit is exactly what you want. This all-in-one reverse-phase mAb analysis kit comes with three identical BioResolve RP mAb Polyphenyl Columns packed with sorbent from three different batches to ensure you can rapidly reproduce separations with the utmost confidence. In addition to the columns, we’ve also included three vials each of the Intact mAb Mass Check Standard and mAb Subunit Standard. These standards can help you benchmark LC-MS system and instrument performance before moving forward with your separations. What’s more, these columns contain features to help you overcome analytical challenges inherent in antibody drug conjugate analysis. Add the BioResolve RP mAb Polyphenyl Method Validation Kit to your lab’s toolkit today and get back to the important analyses of tomorrow.

Included in every BioResolve RP mAb Polyphenyl Method Validation Kit are three BioResolve RP mAb Polyphenyl Columns for your separations. To achieve such great throughput and selectivity, the BioResolve RP mAb Polyphenyl Column contains a group of superficially-porous silica particles that are then functionalized by a novel polyphenyl bonding process. This process is designed specifically for the LC-MS or LC analyses of intact IgG monoclonal antibodies and their fragments, plus this high-coverage bonding helps you to take advantage of increased low pH stability. It’s clear from the moment that you work with these breakthrough chromatography columns that you can maximize the resolving power and selectivity of analyzed protein samples with them. Simply tell your lab manager that the BioResolve RP mAb Polyphenyl Method Validation Kit is needed for your assays.

Protecting your BioResolve RP mAb Polyphenyl Columns from contamination should always be at the forefront of your mind. Whether you’re loading purified samples or connecting equipment, it’s important to ensure no contaminants enter your column and foul it. To prevent contaminants from doing that, we’re happy to provide a solution with the BioResolve RP mAb Polyphenyl VanGuard Cartridge. This breakthrough column protection solution filters out contaminants in the mobile phase stream before they reach your analytical column and cause data variability.

At Waters, we offer solution kits just like the BioResolve RP mAb Polyphenyl Method Validation Kit, but we also offer a vast selection of other products and resources to enhance lab productivity. Shop lab equipment to discover everything we have to offer.

Is the Intact mAb Mass Check Standard Included with the BioResolve RP mAb Polyphenyl Method Validation Kit?

Yes, three vials of the Intact mAb Mass Check Standard are included with the BioResolve RP mAb Polyphenyl Method Validation Kit.