SKU: 186008212
XBridge Oligonucleotide BEH C18 OBD Prep Column, 130Å, 2.5 µm, 10 mm X 50 mm, 1/pk

XBridge Oligonucleotide BEH C18 OBD Prep Column | 186008212


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Product Description

Waters Oligonucleotide Separation Technology columns are based on the second generation of hybrid-silica BEH Technology particles functionalized with C18. The separation of detritylated synthetic oligonucleotide samples is based on the well-established method of ion-pair, reversed-phase chromatography. The availability of 1.7µm UPLC technology or 2.5µm HPLC particles in various column dimensions provides flexibility to meet various laboratory-scale isolation or analysis needs and delivers exceptional sample resolution and superior column life. In addition, Waters manufacturing and quality control testing procedures help ensure consistent batch-to-batch and column-to-column performance regardless of application demands.

Specifications

  • Chemistry

    C18

  • Separation Mode

    Reversed Phase

  • Particle Substrate

    Hybrid

  • pH Range Min

    1 pH

  • pH Range Max

    12 pH

  • Endcapped

    Yes

  • Silanol Activity

    Low

  • Particle Shape

    Spherical

  • Particle Size

    2.5 µm

  • Endfitting Type

    Waters

  • Pore Size

    130 Å

  • QC Tested

    Oligonucleotide

  • Format

    OBD Prep Column

  • Surface Area

    185

  • System

    HPLC

  • Particle Technology

    BEH

  • USP Classification

    L1

  • Inner Diameter

    10 mm

  • Length

    50 mm

  • Carbon Load

    18 %

  • UNSPSC

    41115709

  • Application

    Oligonucleotide, Cell & Gene Therapy

  • Brand

    XBridge

  • Product Type

    Preparative Columns

  • Units per Package

    1 pk

Product Support

Documents

Documents



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XBridge Oligonucleotide BEH C18 OBD Prep Column, 130Å, 2.5 µm, 10 mm X 50 mm, 1/pk

Leverage longer column lifetime and increase your productivity through higher recoveries with the XBridge Oligonucleotide BEH C18 OBD Prep Column. You get exceptional resistance to mechanical chromatographic bed failure with the XBridge Oligonucleotide BEH C18 OBD Prep Column as its Optimum Bed Density (OBD) design is specially formulated to exhibit integrity and stability required in a preparative column used in rapid, high-purity, compound isolations.

Maximize your productivity when scaling up screening methods using the XBridge Oligonucleotide BEH C18 OBD Prep Column. With this lab equipment, you can screen with high resolution and speed from UPLC/HPLC technology. In addition to this, with the XBridge Oligonucleotide BEH C18 OBD Prep Column, you also have the ability to directly scale from UPLC or HPLC screening to lab-scale purification.

Like all Waters equipment, the XBridge Oligonucleotide BEH C18 OBD Prep Column is manufactured using the strictest manufacturing conditions such as the cGMP, ISO 9001:2000 using ultra-pure reagents. This ensures that you get consistent column-to-column performance, reducing the costs through extended lifetimes.

Use our catalog to find varieties of this product with different specifications, and explore more information on our product offerings and available technology. Our online catalog also contains information regarding contacting our various offices for assistance and enables you to shop for lab equipment.

You may also be interested in the AutoPurification System Standard which is a standard mix used to confirm the benchmark performance of a Preparative/Purification System through fraction collection. This AutoPurification Dye Standard contains 3 compounds namely, Thionin, Thioflavin, and Crystal Violet. This particular QCRM has been specially formulated to allow the user to verify correct fraction collection. This test is highly valuable any time the system has not been used or has had any changes as well as to perform upon first use/installation.

Why Are Oligonucleotides Relevant?

Oligonucleotides are a group of short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testing, research, and forensics. In nature, they are usually found as small RNA molecules that function in the regulation of gene expression. They are also degradation intermediates derived from the breakdown of larger nucleic acid molecules. They can also be manufactured as single-stranded molecules with any user-specified sequence in the laboratory by solid-phase chemical synthesis.