What Are The Best Techniques For Isolating And Cleaning Analytes?

To isolate and purify specific components of interest from a sample, two common solid-phase extraction (SPE) techniques are employed. When the concentrations of target chemicals are below the limit of accurate quantification, the retention-cleanup-elution approach is usually adopted. This method enables the concentration of diluted samples and the enrichment of trace chemicals. Alternatively, if the desired sample component is present in high concentration, a pass-through cleanup method may be utilized. However, it's important to note that the pass-through cleanup approach does not result in sample enrichment.