CORTECS HILIC Method Validation Kit, 90Å, 1.6 µm, 2.1 mm X 100 mm, 3/pk

You can easily obtain great levels of efficiency and performance when resolving difficult blends or maintaining resolution while boosting throughput by using the CORTECS HILIC Method Validation Kit. In comparison to normal C18 columns, the CORTECS HILIC Column possesses orthogonal selectivity. It is a high-efficiency column with a solid-core particle that has been designed to retain strongly polar analytes, making it a valuable piece of laboratory equipment.

Count on the CORTECS HILIC Method Validation Kit to deliver faster separations and higher throughput. Because reversed-phase uses unbonded solid-core particles, the lab equipment uses the Hydrophilic Interaction Chromatography (HILIC) mode, which was designed to retain polar compounds when reversed-phase couldn't. The column is extremely stable and retains its shape. In contrast to reversed-phase chromatography, which uses a highly watery mobile phase for the retention of polar analytes, HILIC uses mobile phases with a high concentration of organic solvent. It can now work directly with SPE eluates, resulting in faster sample preparation and higher throughput. Higher organic solvent contents allow for more effective analyte desolvation in the MS source, resulting in improved MS sensitivity and responsiveness.

The solid-core particles in the CORTECS HILIC lab equipment increase performance by lowering each of the van Deemter equation's three terms. The A term falls as the solid core particles pack more uniformly. The B term is lowered because the solid core particles have a lower particle porosity. As a result, axial diffusion is reduced. Their solid core improves heat transfer and eliminates radial temperature gradients, which lowers the C term.

Waters strongly recommends that you keep undesirable physical and chemical pollutants out of your column using the CORTECS HILIC VanGuard Pre-column, 90Å, 1.6 µm, 2.1 mm X 5 mm, 3/pk. The pre-column is made using the exact packing materials that are present in the column and works by connecting with it. It prevents pollutants from entering the mobile phase.