Columns for Antibody Drug Conjugates (ADC)

SKU: 186007104
CORTECS HILIC Column, 90Å, 1.6 µm, 2.1 mm X 50 mm, 1/pk

CORTECS HILIC Column | 186007104


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Product Description

CORTECS HILIC Columns are high-effiency columns based on a solid-core particle that are designed to retain extremely polar analytes. They offer orthogonal selectivity vs. C18 columns.

Specifications

  • Chemistry

    HILIC

  • Separation Mode

    Hydrophilic Interaction (HILIC)

  • Particle Substrate

    Silica

  • pH Range Min

    1 pH

  • pH Range Max

    5 pH

  • Temperature Limits

    45 C

  • Maximum Pressure

    18000 psi (1240 Bar)

  • Endcapped

    No

  • Silanol Activity

    High

  • Particle Shape

    Spherical

  • Particle Size

    1.6 µm

  • Endfitting Type

    Parker-style

  • Pore Size

    90 Å

  • Format

    Column

  • Surface Area

    100

  • System

    UHPLC, UPLC

  • Particle Technology

    Solid Core

  • USP Classification

    L3

  • Inner Diameter

    2.1 mm

  • Length

    50 mm

  • eCord

    Yes

  • UNSPSC

    41115709

  • Brand

    CORTECS

  • Product Type

    Columns

  • Units per Package

    1 pk

Product Support

Documents

Documents



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CORTECS HILIC Column, 90Å, 1.6 µm, 2.1 mm X 50 mm, 1/pk

You can easily obtain great levels of efficiency and performance when resolving difficult blends or maintaining resolution while boosting throughput by using the Waters CORTECS HILIC Column. In comparison to normal C18 columns, the CORTECS HILIC Column possesses orthogonal selectivity. It is a high-efficiency column with a solid-core particle that is designed to hold strongly polar analytes, making it a valuable piece of lab equipment.

Count on the Waters CORTECS HILIC Column to produce faster separations and higher throughput. Because reversed-phase uses unbonded solid-core particles, the lab equipment uses the Hydrophilic Interaction Chromatography (HILIC) mode, which was designed to retain polar compounds when reversed-phase was not able to. In addition, the column has a high level of stability and retention. In contrast to reversed-phase chromatography, which uses a highly watery mobile phase for the retention of polar analytes, HILIC uses mobile phases with a high concentration of organic solvent. It can now work directly with SPE eluates, resulting in faster sample preparation and higher throughput. Higher organic solvent contents allow for more effective analyte desolvation in the MS source, resulting in improved MS sensitivity and responsiveness.

The Waters CORTECS HILIC Column is based on a solid-core particle that has been engineered to hold extremely polar analytes; thus, it is a great addition to your lab equipment collection. In comparison to C18 columns, the CORTECS HILIC Column provides orthogonal selectivity.

The solid-core particles in the CORTECS HILIC Column increase performance by lowering each of the van Deemter equation's three terms. The A term decreases as the solid core particles pack more uniformly. The B term is lowered because the solid core particles have a lower particle porosity. As a result, axial diffusion is reduced. Their solid core improves heat transfer and eliminates radial temperature gradients, which lowers the C term.

The CORTECS HILIC Column, like all Waters equipment, is built to the highest standards in stringent and controlled surroundings to ensure that you receive only the greatest quality products.

Protect your high-efficiency analytical lab equipment from harm by using the CORTECS HILIC VanGuard Pre-column, 90Å, 1.6 µm, 2.1 mm X 5 mm, 3/pk.

What pH Range Is Applicable To The CORTECS HILIC Column?

This particular CORTECS HILIC Column offers a pH range of 1-5.