Chemistry |
C18 |
Separation Mode |
Reversed Phase |
Particle Substrate |
Hybrid |
pH Range Min |
1 pH |
pH Range Max |
11 pH |
Maximum Pressure |
18000 psi (1240 Bar) |
Endcapped |
Yes |
Silanol Activity |
Low |
Particle Shape |
Spherical |
Particle Size |
1.7 µm |
Endfitting Type |
Parker-style |
Pore Size |
130 Å |
Format |
Column |
Surface Area |
185 |
System |
UHPLC, UPLC |
Particle Technology |
CSH |
USP Classification |
L1 |
Inner Diameter |
3 mm |
Length |
75 mm |
Carbon Load |
15 % |
eCord |
Yes |
UNSPSC |
41115709 |
Brand |
ACQUITY UPLC |
Product Type |
Columns |
Units per Package |
1 pk |
ACQUITY UPLC CSH C18 Column, 130Å, 1.7 µm, 3 mm X 75 mm, 1/pk
Waters created the ACQUITY UPLC CSH C18 Column in response to feedback gathered at numerous customer forums. When compared to other reversed-phase UPLC columns, the ACQUITY UPLC CSH C18 Column was created to offer a different level of selectivity. These incredibly effective lab equipment overcome column bleed, quick mobile-phase re-equilibration, peak shape asymmetry, and limited loading capacity for basic chemicals. The Charged Surface Hybrid (CSH) Technology, which is the next step in particle technology, is the main driving force behind the ACQUITY UPLC CSH columns. The Charged Surface Hybrid (CSH) Technology, which is the primary working principle of the ACQUITY UPLC CSH columns, was created by Waters.
Since the ACQUITY UPLC CSH C18 Column uses CSH Technology, which provides Trifluoroacetic Acid (TFA) peak shape performance without the use of TFA, method development is quicker and simpler. Trifluoroacetic acid can provide crisp peak forms for basic chemicals, but it is a difficult ion-pairing agent to get rid of from the ACQUITY phase of a liquid chromatography lab equipment once it has been exposed to it. In contrast, the ACQUITY UPLC CSH C18 Column can produce better peak shape performance when using mobile phase additives that are favorable to MS, like formic acid. As formic acid does not exhibit the effects of an ion-pairing agent, this also leads to quicker and simpler technique creation.
In contrast to the two ACQUITY brands from Waters, the ACQUITY UPLC BEH and XBridge, the ACQUITY UPLC CSH C18 Column offers alternative selectivity, a larger range, and a unique design. The ACQUITY UPLC CSH C18 Column offers a wide range of selectivities without sacrificing essential performance characteristics like peak shape for basic chemicals, minimum column bleed, and seamless transferability between various particle sizes and column formats.
We recommend that you protect your analytical column by opting for the ACQUITY UPLC CSH C18 VanGuard Pre-column, 130Å, 1.7 µm, 2.1 mm X 5 mm, 3/pk.
What Is The ACQUITY UPLC CSH C18 Column’s pH Range?
The ACQUITY UPLC CSH C18 Column listed here is able to offer a wide pH range of 1-11.
What Is The Maximum Pressure That The ACQUITY UPLC CSH C18 Column Can Sustain?
This particular ACQUITY UPLC CSH C18 Column can tolerate a maximum of 18,000 psi (1240 Bar).