Waters offers a comprehensive range of analytical system solutions, software, and services for scientists. Liquid Chromatography. Mass Spectrometry. Waters is the leading provider of lab equipment, supplies and software for scientists across the world. Easily research and order everything your lab needs! Waters offers a comprehensive range of analytical system solutions, software, and services for scientists. Liquid Chromatography. Mass Spectrometry. Waters is the leading provider of lab equipment, supplies and software for scientists across the world. Easily research and order everything your lab needs!
SKU: 186005302 ACQUITY UPLC CSH C18 Column, 130Å, 1.7 µm, 3 mm X 150 mm, 1/pk
ACQUITY CSH C18 columns were designed to provide alternate selectivity compared to other reversed-phase UPLC columns. These ultra-efficient columns overcome peak shape asymmetry and poor loading capacity for basic compounds, column bleed, and rapid mobile-phase re-equilibration.
ACQUITY UPLC CSH C18 Column, 130Å, 1.7 µm, 3 mm X 150 mm, 1/pk
Waters created the ACQUITY UPLC CSH C18 Column in response to feedback gathered at numerous customer forums. When compared to other reversed-phase UPLC columns, the lab equipment was created to offer a different level of selectivity. These incredibly effective columns overcome column bleed, quick mobile-phase re-equilibration, peak shape asymmetry, and limited loading capacity for basic chemicals. The Charged Surface Hybrid (CSH) Technology, which is the next step in particle technology, is the main driving force behind the ACQUITY UPLC CSH columns. The Charged Surface Hybrid (CSH) Technology, which is the primary working principle of the ACQUITY UPLC CSH columns, was created by Waters.
Since the ACQUITY UPLC CSH C18 Column uses CSH Technology, which provides Trifluoroacetic Acid (TFA) peak shape performance without the use of TFA, method development is quicker and simpler. Trifluoroacetic acid can provide crisp peak forms for basic chemicals, but it is a difficult ion-pairing agent to get rid of from the ACQUITY phase of a liquid chromatography column once it has been exposed to it. In contrast, the ACQUITY UPLC CSH C18 Column can produce better peak shape performance when using mobile phase additives that are favorable to MS, like formic acid. This also results in the faster and more straightforward method development as formic acid does not show the effects of an ion-pairing agent. Additionally, the lab equipment provides increased analytical loadability, delivering sharper, narrower peaks for basic compounds under the acidic, low ionic strength mobile phase conditions. The columns are also ideally suited for isolation and purification as the increased loadability allows for the use ofa narrower preparative column, reducing solvent consumption and fraction volumes.
In contrast to the two ACQUITY brands from Waters, the ACQUITY UPLC BEH and XBridge, the ACQUITY UPLC CSH C18 Column offers alternative selectivity, a larger range, and a unique design. The ACQUITY UPLC CSH C18 Column offers a wide range of selectivities without sacrificing essential performance characteristics like peak shape for basic chemicals, minimum column bleed, and seamless transferability between various particle sizes and column formats.
