Symmetry Shield RP18 Prep Guard Cartridge, 100Å, 5 µm, 19 mm X 10 mm, 1/pk

Using the same C18 column time and again in the lab can unfortunately cause data variability if the column isn’t cleaned properly each time. But what about the sample you’re using?
The sample can cause the fouling as well, which is why the we recommend you equip your column with the Symmetry Shield RP18 Prep Guard Cartridge. This HPLC guard cartridge is only one part of the preparative HPLC workflow. Please discuss with your lab manager about which other parts to buy in conjunction with the Symmetry Shield RP18 Prep Guard Cartridge.

It’s important to reduce silanol activity as much as possible when performing LC-MS analysis, and the Symmetry Shield RP18 Column offers an embedded polar technology that shields the interior of the column from basic analytes. And when the preparative guard cartridge has been properly equipped, the risk of silanol activity is further reduced. This will also help to improve overall peak shape, leading to a data set you can easily verify and re-verify if needed.

What makes Symmetry Shield different?
For one thing, Symmetry HPLC Columns offer a narrow column specification, which makes data variation much less of a worry. In addition, if you’re working with peptide applications, there’s a Symmetry Column that’s right for your needs. And when equipped with a prep guard cartridge, you’ll be protecting your precious data even more from various conditions.

Another major factor dictating data reliability is overall system performance. If your LC-MS system hasn’t been calibrated lately, we highly recommend doing so before using the Symmetry Shield RP18 Prep Guard Cartridge. Did you run out of reference materials?
That’s no concern when you turn to the experts at Waters, as we have a complete and thorough collection of QC reference materials that can be used with any chromatographic system that contains a UV detector. Add Neutrals QC Reference Material to your lab’s toolkit to make benchmarking even easier. Don’t forget to explore our other QC reference materials for sale.

At Waters, it’s our passion to help scientists achieve success through our breakthrough products and resources. From full LC-MS systems to standards and reagents, we’re your one-stop shop for your lab. Shop lab equipment now to find everything you’ll ever need in the lab.