Chemistry |
C4 |
Separation Mode |
Reversed Phase |
Particle Substrate |
Silica |
pH Range Min |
2 pH |
pH Range Max |
8 pH |
Maximum Pressure |
6000 psi (415 Bar) |
Endcapped |
Yes |
Silanol Activity |
Low |
Molecular Weight Range Min |
1000 |
Molecular Weight Range Max |
30000 |
Particle Shape |
Spherical |
Particle Size |
3.5 µm |
Endfitting Type |
Waters |
Pore Size |
300 Å |
Format |
Column |
Surface Area |
110 |
System |
HPLC |
USP Classification |
L26 |
Inner Diameter |
4.6 mm |
Length |
150 mm |
Carbon Load |
2.8 % |
UNSPSC |
41115709 |
Application |
Protein |
Brand |
Symmetry |
Product Type |
Columns |
Units per Package |
1 pk |
Symmetry C4 Column, 300Å, 3.5 µm, 4.6 mm X 150 mm, 1K - 30K, 1/pk
When compared to conventional columns of similar chemistry, the Symmetry C4 Column provides improved peak shape and peak capacity for the separation of physiologically active peptides. The Waters Symmetry C4 Column outperforms other columns when it comes to separating hydrophilic and hydrophobic peptides, as well as neutral and highly basic peptides.
With the Symmetry C4 Column, which has been intended to set the standard for HPLC drug testing, you can have trust in the long-term compliance of your HPLC procedures. The lab equipment allows critical analysis to be performed without sacrificing peak shape, selectivity, column-to-column and batch-to-batch consistency, or other critical performance parameters. The wide-pored, reversed-phase Symmetry C4 Column is a popular choice in the pharmaceutical business because of its sensitive, robust, and rough HPLC testing. Large peptides and proteins benefit from its C4 chemistry.
Waters Symmetry columns continue to set the standard for HPLC drug assays, giving you confidence in the long-term compliance of your HPLC methods. Available in a variety of particle sizes, chemistries, and dimensions. You can explore all variations of the lab equipment from our website, as well as purchase directly from us.
Get the finest peaks for biomolecules and higher peak capacity for complicated tryptic maps with the Symmetry C4 Column. This is made possible by the use of ultrapure agents to manufacture the silica. As a result, an analytical column with a high purity and low silanol activity has been created. The column is also packed to the best efficiency and reproducibility of any product on the market, providing better precision for impurity and stability assays, more precise quantitation, and adaptation to more demanding techniques.
Waters recommends that you protect your analytical column using the Waters Symmetry C4 Sentry Guard Cartridge, 300Å, 3.5 µm, 2.1 mm X 10 mm, 1K - 30K, 2/pk. Made using the exact same packing materials that are present in the analytical column, the cartridge works by preventing any particulate or chemical pollutants from entering the mobile stream.
Across What pH Range Does The Symmetry C4 Column Operate?
The Symmetry C4 Column listed here works well across the 2-8 pH range.
What Maximum Pressure Can The Symmetry C4 Column Sustain?
This particular Symmetry C4 Column is able to work well with up to 6000 psi (415 Bar) pressure.