BioResolve SEC Column 7.8x150 mm Guard 4.6x30 mm mAb Size Variant Standard 176004598

SKU: 176004598
BioResolve SEC mAb Column with BioResolve SEC mAb Guard, 200Å, 2.5 µm, 7.8 x 150 mm, 1/pk with mAb Size Variant Standard

BioResolve SEC mAb Column with BioResolve SEC mAb Guard | 7.8 x 150mm | 176004598


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Product Description

Primarily supports legacy methods. The BioResolve SEC mAb 7.8 x 150 mm Column and Guard contains 2.5 µm BEH particle technology and is application specifically tested with the mAb Size Variant Standard to ensure accurate and highly reproducible quantitation of monoclonal antibody (mAb) monomers from frequently associated high molecular weight aggregates (≥300,000 Da) and lower molecular weight fragments (e.g., ≤100,000 Da). This column is also shipped with Water mAb Size Variant Standard at no extra charge (p/n: 176004593)

Specifications

  • Chemistry

    SEC

  • Separation Mode

    SEC

  • Particle Substrate

    Hybrid

  • pH Range Min

    2.5 pH

  • pH Range Max

    8 pH

  • Temperature Limits

    60 C

  • Maximum Pressure

    4500 psi (310 Bar)

  • Endcapped

    No

  • Bonding Technology

    Diol (OH)

  • Silanol Activity

    Low

  • Molecular Weight Range Min

    10000

  • Molecular Weight Range Max

    450000

  • Particle Shape

    Spherical

  • Particle Size

    2.5 µm

  • Endfitting Type

    Parker-style

  • Pore Size

    200 Å

  • QC Tested

    Protein

  • Format

    Online Column

  • Packing Solvent

    10% acetonitrile/90% 25 mM sodium phosphate pH 7.0 + 100 mM KCl

  • Surface Area

    220

  • System

    HPLC

  • Particle Technology

    BEH

  • Technique

    LC

  • USP Classification

    L33

  • Inner Diameter

    7.8 mm

  • Length

    150 mm

  • Carbon Load

    12 %

  • eCord

    Yes

  • UNSPSC

    41115711

  • Application

    Protein

  • Brand

    BioResolve

  • Product Type

    Columns

  • Units per Package

    1 pk

Product Support

Documents

Documents



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BioResolve SEC mAb Column with BioResolve SEC mAb Guard, 200Å, 2.5 µm, 7.8 x 150 mm, 1/pk with mAb Size Variant Standard

Monoclonal antibody separations requires unique selectivity that only certain columns can provide, but the BioResolve SEC mAb Column is here to provide that and so much more. This monoclonal antibody column can deliver accurate and reproducible quantification of monoclonal antibodies, and it also comes with the BioResolve SEC mAb Guard to better protect your column from contaminants in the mobile phase stream. What’s more, if you need to verify system performance for mAb-related assays, know that this column also comes with the Waters mAb Size Variant Standard at no extra charge. See how the BioResolve SEC mAB Column can improve your mAb separations and analyses by adding one to your lab’s toolkit today.

To overcome common biological separation challenges, the BioResolve SEC mAb Column incorporates many different desirable features. For one, it offers a wide and usable pH range that can accommodate the various analytes you’ll need to use. But if you take a look at the BioResolve SEC mAb Column specifications, you’ll also see that this column can uphold mechanical stability despite the incredible backpressures needed for separations. This especially comes in handy when you need to quickly reproduce to verify your data.

How can you be sure of the BioResolve SEC mAb Column’s performance?
This flexible column is tested with the mAb Size Variant Standard to ensure it’s operating exactly as it should. This way you can be sure of its capabilities right out of the shipping box. But what about column contamination concerns?
To meet those concerns head-on, we’ve included the BioResolve SEC mAb Guard. This guard column acts an extra step of protection against contaminants that may be lingering in the mobile phase stream. This is no replacement for sample purification protocols, of course, but this guard can help significantly increase your column’s performance over its entire lifetime.

At Waters, we have much more than just columns to help you overcome biological separation challenges. We also have full LC-MS systems, sample preparation kits, method development kits, quality control reference materials and everything else you’ll need to be successful in the lab. It’s our passion to provide the essentials and new technology to help you improve your internal workflows. Shop lab equipment to see how our products and resources can help push your lab into the future.

What’s the BioResolve SEC mAb Column’s pH Range?

The BioResolve SEC mAb Column offers a range of 2.5 to 8 pH.