BioResolve SCX mAb, 3 μm, corrosion–resistant columns which contain non-porous, polymer-based particles grafted with a rigorously-optimized, multi-component network of negatively charged sulfonic acid ligands. This innovative column technology, delivers reproducible, high-resolution, charged-based separations of mAbs and other proteins in both LC and LC-MS applications using robust salt or pH gradient methods. This Method Validation Kit (MVK) contains three columns from three different batches. This P/N also contains three vials of the mAb Charge Variant Standard (P/N 186009065)
pH Range Min |
3 pH |
Bonding Technology |
SCX |
Particle Shape |
Spherical |
Particle Size |
3 µm |
QC Tested |
Protein |
Format |
Column |
System |
HPLC, UHPLC, UPLC |
Inner Diameter |
2.1 mm |
Length |
100 mm |
eCord |
Yes |
UNSPSC |
41115709 |
Application |
Protein |
Brand |
BioResolve |
Product Type |
Columns |
Units per Package |
3 pk |
BioResolve SCX mAb Method Validation Kit, 3 µm, 2.1 mm x 100 mm, 3/pk with mAb Charge Variant Standard
Strong cation-exchange chromatography is commonly used for monoclonal antibody quantitation, especially since it allows charge variant analysis to be used as well. And with the BioResolve SCX mAb Method Validation Kit, you get everything you need to properly harness the selectivity and power of charge variant analysis of monoclonal antibodies. This mAb solutions kit comes with three identical BioResolve SCX mAb Columns packed with the same sorbent so you can quickly perform separations and validate your method by doing so. Speaking of performance, we’ve also included the Waters Charge Variant Standard free of charge so you can verify system and instrument performance when needed. Upgrade your monoclonal antibody analyses with the help of the BioResolve SCX mAb Method Validation Kit today.
The charge variant analysis of monoclonal antibodies and other proteins is a critical quality attribute to understand, but the BioResolve SCX mAb Column makes easy work of the performance side of things. That’s because this column comes with non-porous, polymeric particles that help to reduce band spread and improve performance for mAb separations. These particles are grafted onto a network of sulfonic acid ligands to become incredibly resistant to corrosion as well. This will help to extend your column’s overall lifetime.
Speaking of overall column lifetimes, protecting your BioResolve SCX mAb Columns from contaminants should always be a top priority. To achieve the level of protection you need from particulate contaminants and fragments, we recommend adding the BioResolve SCX mAb VanGuard FIT Cartridge to your analytical workflow. This cartridge is incorporated seamlessly and upholds both chemical and mechanical stability. Plus, when the cartridge itself has become worn and needs to be replaced, you can do so with another genuine guard cartridge from Waters. It’s important to note that this column protection solution is no replacement for following proper sample preparation protocols.
Ready to perform the mAb analyses that matter?
Before checking out with your BioResolve SCX mAb Method Validation Kit, make sure to explore all of our other products and resources. We truly have everything you need to be successful in the lab, from lab informatics to quality control reference materials and solution kits. Shop lab equipment to review our offerings.
What Does the “SCX” in BioResolve SCX mAb Column Mean?
Strong cation-exchange.