SCX Start Up Kit: BioResolve SCX mAb Column (2.1 mm x 50 mm) with mAb Standard plus pH Concentrates

The 3 μm BioResolve SCX mAb columns are corrosion-resistant and contain non-porous polymer-based particles that have been rigorously optimized to include a multi-component network of negatively charged sulfonic acid ligands. Using reliable salt or pH gradient approaches, this cutting-edge column technology achieves reproducible, high-resolution, charged-based separations of mAbs and other proteins in both LC and LC-MS applications. Additionally, this startup kit comes with two Certified LDPE 1000 mL Containers made for use with Water BioResolve CX Buffer Concentrates, one vial of the mAb Charge Variant Standard (P/N 186009065), one bottle each of BioResolve CX pH Concentrate A (pH 5.0) and B (pH 10.2), and one vial of the mAb Charge Variant Standard.

A wide variety of monoclonal antibodies are frequently separated properly and consistently with charge variant quantification using strong cation-exchange analysis. However, a chromatography column that can easily tolerate chromatographic conditions is required for SCX analysis to be successful. The BioResolve SCX mAb Column provides the flexibility and stiffness you need to get beyond those obstacles. And because this column offers charge variation analysis of mAbs and other proteins, we provide LC-MS users with a platform that uses strong salt and pH gradient techniques to boost your analyses.

The non-porous polymeric particles inside the BioResolve SCX mAb Column actively strive to reduce analyte band spread to increase mAb separations, which also gives you superior component recovery, peak shape, and component resolution. And because we care so much about how you use this column for method development, we have set it up to have a low injection-to-injection carryover rate during method transfer. In addition to this, this lab equipment is LC system independent, allowing for unrestricted use on all UHPLC, HPLC, and UPLC systems. You can repeatedly obtain strong and high-resolution mAb separations in this method.

Waters provides much more than only BioResolve SCX mAb Columns to help you comprehend the creation of biotherapeutic drugs. Shop for lab equipment to equip your lab with all you need.

You may also be interested in the BioResolve SCX mAb VanGuard FIT Cartridge.