SKU: 176004353
SCX Start Up Kit: BioResolve SCX mAb Column (4.6 mm X 50 mm) with VanGuard FIT plus mAb Standard plus pH Concentrates

SCX Start Up Kit: BioResolve SCX mAb Column | 4.6 x 50mm | 176004353


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Product Description

BioResolve SCX mAb, 3 μm, corrosion–resistant columns which contain non-porous, polymer-based particles grafted with a rigorously-optimized, multi-component network of negatively charged sulfonic acid ligands. This innovative column technology, delivers reproducible, high-resolution, charged-based separations of mAbs and other proteins in both LC and LC-MS applications using robust salt or pH gradient methods.  In addition, this offering includes VanGuard™ Fully Integrated Technology (FIT) that maximizes column life without degrading biomolecule component resolution.  This startup kit also includes one vial of the mAb Charge Variant Standard (P/N 186009065), one bottle of the BioResolve CX pH Concentrate A (pH 5.0) and one bottle of the BioResolve CX pH Concentrate B (pH 10.2), and  two of the Certified LDPE 1000 mL Containers designed for use with Water BioResolve CX Buffer Concentrates.

Specifications

  • pH Range Min

    3 pH

  • Bonding Technology

    SCX

  • Particle Shape

    Spherical

  • QC Tested

    Protein

  • Format

    Column

  • System

    HPLC, UHPLC, UPLC

  • Inner Diameter

    4.6 mm

  • Length

    50 mm

  • eCord

    Yes

  • UNSPSC

    41115709

  • Application

    Protein

  • Brand

    BioResolve

  • Product Type

    Columns

Product Support

Documents

Documents



What do you want to do?

What do you want to do?
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SCX Start Up Kit: BioResolve SCX mAb Column (4.6 mm X 50 mm) with VanGuard FIT plus mAb Standard plus pH Concentrates

For monoclonal antibody analysis via strong cation-exchange chromatography to be successful, you need the right analytical instrument and the pH concentrates to help implement charge variant profiling. That’s where the SCX Start Up Kit comes into consideration. This kit is filled with all of the essentials you need for SCX mAb analysis, including two BioResolve SCX mAb Columns, two VanGuard FIT Cartridges, one bottle each of BioResolve Concentrates A and B, as well as the mAb Charge Variant Standard. And if that isn’t enough to convince you of this kit’s capabilities, know that the VanGuard FIT Cartridges can maximize column life without degrading biomolecule component resolution. Take your mAb analyses to the next level with the SCX Start Up Kit.

Although the BioResolve SCX mAb Columns are know for their ability to reliably separate, with charge variant quantitation, a wide range of mAbs, the technology that enables them to do so is even more interesting. Within each BioResolve SCX mAb Column is a group of non-porous, polymeric particles that work hard to reduce band spread and increase resolution whenever possible. Not only that, but they also enable superior component recovery and peak shape. That kind of dedication to perfection in monoclonal antibody quantitation is only of the many reasons why scientists turn to the BioResolve SCX mAb Column for biotherapeutic drug analysis.

Before performing any monoclonal antibody separations with the BioResolve SCX mAb Columns, make sure the BioResolve SCX mAb VanGuard Cartridges are properly installed and in working order. These cartridges remove particulate contaminants from the mobile phase stream as it flows through it, plus it offers the same inner diameter and pH range as your analytical column. This helps to provide a chemically and mechanically stable column protection solution. And speaking of doing things before performing separations, make sure to verify LC-MS system and instrument performance with the mAb Charge Variant Standard that’s included in the SCX Start Up Kit.

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How Can I Easily Implement Charge Variant Profiling in SCX mAb Analysis?

With the BioResolve SCX mAb Column and BioResolve CX pH Concentrates, as they work together to provide simple-to-implement charge variant profiling.