BioResolve SCX mAb, 3 μm, corrosion–resistant columns which contain non-porous, polymer-based particles grafted with a rigorously-optimized, multi-component network of negatively charged sulfonic acid ligands. This innovative column technology, delivers reproducible, high-resolution, charged-based separations of mAbs and other proteins in both LC and LC-MS applications using robust salt or pH gradient methods. In addition, this offering includes VanGuard™ Fully Integrated Technology (FIT) that maximizes column life without degrading biomolecule component resolution. This Method Validation Kit (MVK) contains three columns from three different batches. This P/N also contains three vials of the mAb Charge Variant Standard (P/N 186009065)
pH Range Min |
3 pH |
Bonding Technology |
SCX |
Particle Shape |
Spherical |
Particle Size |
3 µm |
QC Tested |
Protein |
Format |
Column |
System |
HPLC, UHPLC, UPLC |
Inner Diameter |
4.6 mm |
Length |
100 mm |
eCord |
Yes |
UNSPSC |
41115709 |
Application |
Protein |
Brand |
BioResolve |
Product Type |
Columns |
Units per Package |
3 pk |
BioResolve SCX mAb Method Validation Kit with VanGuard FIT, 3 µm, 4.6 mm X 100 mm, 3/pk with mAb Charge Variant Standard
Charge variant analysis helps scientists across the globe perform monoclonal antibody analysis successfully, but you need a separation instrument that’s more than capable of handling demanding chromatographic conditions. With the BioResolve SCX mAb Method Validation Kit, you get three BioResolve SCX mAb Columns to help you validate your methods. Plus, each of these columns comes equipped with VanGuard FIT technology to protect your data from variability caused by contaminants in the mobile phase stream. Upgrade your mAb analyses with the BioResolve SCX mAb Method Validation Kit today!
The accurate charge variant quantitation of monoclonal antibodies is easily achieved by the BioResolve SCX mAb Column. But how?
This column offers a solution-based platform for LC-MS users by utilizing pH gradient methods and robust salts. Plus, with a wide and usable pH range, it should comes as no surprise that scientists across the world are turning to the BioResolve SCX mAb Column for charge variant analyses.
Another major benefit to owning the BioResolve SCX mAb Method Validation Kit is how the BioResolve SCX mAb Column offers non-porous polymeric particles to reduce band spread and enhanced mAb separations. And when you pair this column with the BioResolve CX pH Concentrate pH 5 and pH 10.2 Kit, you can achieve simple charge variant profiling. This helpful concentrate kit is designed to help optimize a pH 5.0 to 10.2 gradient for mAb charge variant separations.
Not sure which LC-MS systems are compatible with the BioResolve SCX mAb Column?
Luckily for you, this breakthrough separation tool is LC-MS system agnostic, which means it can work with UHPLC, UPLC and HPLC systems with the same level of terrific performance. And when you add the VanGuard FIT guard cartridge to your analytical workflow, you’ll be better protected from data variability.
At Waters, we offer a truly massive selection of products and resources to help you in the lab. From full LC-MS systems to quality control reference materials and sample prep solutions, we truly have it all. Shop lab equipment to discover everything we have to offer.
Which LC-MS Systems Can the BioResolve SCX mAb Column Be Used With?
The BioResolve SCX mAb Column can be used with UHPLC, HPLC and UPLC systems.