BioResolve SCX mAb, 3 μm, corrosion–resistant columns which contain non-porous, polymer-based particles grafted with a rigorously-optimized, multi-component network of negatively charged sulfonic acid ligands. This innovative column technology, delivers reproducible, high-resolution, charged-based separations of mAbs and other proteins in both LC and LC-MS applications using robust salt or pH gradient methods. In addition, this offering includes VanGuard™ Fully Integrated Technology (FIT) that maximizes column life without degrading biomolecule component resolution. This P/N also contains one vial of the mAb Charge Variant Standard (P/N 186009065)
pH Range Min |
3 pH |
Bonding Technology |
SCX |
Particle Shape |
Spherical |
Particle Size |
3 µm |
QC Tested |
Protein |
Format |
Column |
System |
HPLC, UHPLC, UPLC |
Inner Diameter |
4.6 mm |
Length |
100 mm |
eCord |
Yes |
UNSPSC |
41115709 |
Application |
Protein |
Brand |
BioResolve |
Product Type |
Columns |
Units per Package |
1 pk |
BioResolve SCX mAb Column with VanGuard FIT, 3 µm, 4.6 mm x 100 mm, 1/pk with mAb Charge Variant Standard
Monoclonal antibody analysis presents a few unique analytical challenges that even the most knowledgeable scientist must work hard to overcome, and the BioResolve SCX mAb Column is here to help you overcome those challenges. This strong cation-exchange column is uniquely suited for the quantitation of monoclonal antibodies, plus it comes with a VanGuard FIT Cartridge that will protect your data from variability caused by column contamination. What’s more, this column also offers a wide and usable pH range that’s sure to suit the analyte you’ve chosen to use. Add the BioResolve SCX mAb Column to your lab’s toolkit now and change your mAb assays for the better!
To ensure the purity of therapeutic drugs, mAb columns are commonly used. That’s why the BioResolve SCX mAb Column was designed specifically for that kind of analysis. This column’s ability to separate with accurate charge variant quantitation is truly unparalleled, plus you can use this column on any LC-MS system as it’s system agnostic. Want to be sure of this column’s performance?
Each and every BioResolve SCX mAb Column undergoes a strict QC process where it’s tested with the Waters mAb Charge Variant Standard before being packed and shipped to you. This helps us to ensure you only get the best-performing SCX columns right out of the box.
Protecting your precious data from variability should always be at the forefront of your mind. One way that data can be skewed is by particulate contaminants in the mobile phase stream. To meet that challenge head-on, we’re happy to provide the BioResolve SCX mAb VanGuard FIT Cartridge. This guard cartridge seamlessly incorporates into your existing analytical workflow to provide enhanced protection against column contamination. Please note that this cartridge is no replacement for proper column cleaning and regeneration procedures.
Do you need to stock up on system benchmarking standards for mAb assays?
Look no further than the mAb Charge Variant Standard. This helpful standard can be used to verify system performance for strong cation-exchange chromatography.
We offer so much more than just BioResolve SCX mAb Columns and system benchmarking standards, too. If you’re a scientist working with LC-MS systems, you’ll find incredible products and resources to assist your assays at Waters Corporation. You need only shop lab equipment to find our truly massive and essential collection of items.
What is the BioResolve SCX mAb Column Known For?
The BioResolve SCX mAb Column is known for its ability to reliably separate, with accurate charge variant quantitation, a wide range of mAbs using optical or LC-MS compatible mobile phases.