SKU: 176004343
BioResolve SCX mAb Column with VanGuard FIT, 3 µm, 2.1 mm x 100 mm 1/pk with mAb Charge Variant Standard

BioResolve SCX mAb Column with VanGuard FIT | 2.1 x 100mm | 176004343


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Product Description

BioResolve SCX mAb, 3 μm, corrosion–resistant columns which contain non-porous, polymer-based particles grafted with a rigorously-optimized, multi-component network of negatively charged sulfonic acid ligands. This innovative column technology, delivers reproducible, high-resolution, charged-based separations of mAbs and other proteins in both LC and LC-MS applications using robust salt or pH gradient methods.  In addition, this offering includes VanGuard™ Fully Integrated Technology (FIT) that maximizes column life without degrading biomolecule component resolution.  This P/N also contains one vial of the mAb Charge Variant Standard (P/N 186009065)

Specifications

  • pH Range Min

    3 pH

  • Bonding Technology

    SCX

  • Particle Shape

    Spherical

  • Particle Size

    3 µm

  • QC Tested

    Protein

  • Format

    Column

  • System

    UHPLC, UPLC, HPLC

  • Inner Diameter

    2.1 mm

  • Length

    100 mm

  • eCord

    Yes

  • UNSPSC

    41115709

  • Application

    Protein

  • Brand

    BioResolve

  • Product Type

    Columns

  • Units per Package

    1 pk

Product Support

Documents

Documents



What do you want to do?

What do you want to do?
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BioResolve SCX mAb Column with VanGuard FIT, 3 µm, 2.1 mm x 100 mm 1/pk with mAb Charge Variant Standard

Monoclonal antibodies can be quantitated in many different ways, but using charge variant analysis and strong cation-exchange chromatography has often been cited as one of the most desirable methods. That’s why the BioResolve SCX mAb Column is here to change how you use that method forever. This mAb column incorporates a bevy of features to improve selectivity, band spread and performance for mAb separations, plus it can be used on all UHPLC, UPLC and HPLC systems. That kind of flexibility comes in handy when developing successful methods. And to protect your column from contamination, the VanGuard FIT Cartridge for this column is included. Streamline your monoclonal antibody analysis workflow with the help of the BioResolve SCX mAb Column today.

How does the VanGuard FIT Cartridge protect the BioResolve SCX mAb Column from contaminants?
This cartridge acts as an extra step for the mobile phase stream to flow through, filtering out contaminants and removing them before they reach your analytical column. And since the guard cartridge offers the same inner diameter and packing material as the BioResolve SCX mAb Column, both chemical and mechanical stability can be easily upheld.

Running through each and every BioResolve SCX mAb Column is a network of negatively charged sulfonic acid ligands. Non-porous, polymeric particles are grafted onto this network of ligands to help minimize analyte band spread, improve performance and give you superior component recovery times. Plus, every single BioResolve SCX mAb Column is QC tested with the Waters Charge Variant Standard to ensure proper performance right out of the box. You can use this standard on your LC-MS systems to verify performance as well.

Looking for even more ways to upgrade your mAb separations?
Purchase the IonHance CX-MS pH Concentrates A & B Kit. This kit of pH buffers can help you establish easy-to-implement charge variant profiling, so you can quickly reproduce and validate methods as needed.

Once you’ve added the BioResolve SCX mAb Column to your cart, make sure to shop lab equipment to explore the rest of our offerings. We have everything from lab informatics to quality control reference materials and so much more.

What’s the BioResolve SCX mAb Column’s pH Range Minimum?

The BioResolve SCX mAb Column offers a pH range minimum of 3 pH.