SKU: 176004341
BioResolve SCX mAb Column with VanGuard FIT, 3 µm, 2.1 mm x 50 mm, 1/pk with mAb Charge Variant Standard

BioResolve SCX mAb Column with VanGuard FIT | 2.1 x 50mm | 176004341


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Product Description

BioResolve SCX mAb, 3 μm, corrosion–resistant columns which contain non-porous, polymer-based particles grafted with a rigorously-optimized, multi-component network of negatively charged sulfonic acid ligands. This innovative column technology, delivers reproducible, high-resolution, charged-based separations of mAbs and other proteins in both LC and LC-MS applications using robust salt or pH gradient methods.   In addition, this offering includes VanGuard™ Fully Integrated Technology (FIT) that maximizes column life without degrading biomolecule component resolution.  This P/N also contains one vial of the mAb Charge Variant Standard (P/N 186009065)

Specifications

  • pH Range Min

    3 pH

  • Bonding Technology

    SCX

  • Particle Shape

    Spherical

  • Particle Size

    3 µm

  • QC Tested

    Protein

  • Format

    Column

  • System

    HPLC, UHPLC, UPLC

  • Inner Diameter

    2.1 mm

  • Length

    50 mm

  • eCord

    Yes

  • UNSPSC

    41115709

  • Application

    Protein

  • Brand

    BioResolve

  • Product Type

    Columns

  • Units per Package

    1 pk

Product Support

Documents

Documents



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What do you want to do?
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BioResolve SCX mAb Column with VanGuard FIT, 3 µm, 2.1 mm x 50 mm, 1/pk with mAb Charge Variant Standard

Quantitating charge variants in monoclonal antibodies can sometimes be difficult, especially when working with difficult samples. But the BioResolve SCX mAb Column is here to help you conquer all analytical challenges in your way to completing successful monoclonal antibody analysis. What’s more, this strong cation-exchange column comes equipped with a VanGuard FIT Cartridge that will protect your precious data and separations from variability caused by particulate contaminants. Upgrade your assays with the BioResolve SCX mAb Column, or tell your lab manager that you want this breakthrough separation instrument at your command today.

How does the BioResolve SCX mAb Column deliver such great selectivity?
First, this monoclonal antibody analysis column contains non-porous, polymer-based particles that are then grafted onto a network of negatively charged sulfonic acid ligands. This combination of particle technology ensures that you can reliably separate a wide range of mAbs with charge variant quantitation. Plus, it doesn’t matter which LC-MS system you use this column with, as it can be used with UHPLC, UPLC and HPLC systems. This especially comes in handy for method development.

To ensure that you only receive the best-performing SCX column right out of the box, each and every BioResolve SCX mAb Column must undergo a strict QC testing process before being packed and shipped to you. This column is tested with the mAb Charge Variant Standard to ensure proper performance, and you can use the exact same standard to verify LC-MS system and other instrument performance for charge variant analysis.

Protecting your precious data and separations from variability should always be a top priority. Although proper sample purification processes remove many of the particulate contaminants, there still may be contaminants lingering in the mobile phase stream. That’s why we’ve included the BioResolve SCX mAb VanGuard FIT Cartridge to this column, making for a streamlined and protected analytical workflow. This cartridge removes contaminants from the mobile phase stream before they reach your column.

Before checking out with your BioResolve SCX mAb Column with accompanying VanGuard FIT Cartridge, shop lab equipment to discover all of the incredible products and resources we have to offer.

How Can I Test the BioResolve SCX mAb Column for Performance?

The BioResolve SCX mAb Column can be tested for performance using the mAb Charge Variant Standard.