BioResolve RP mAb Columns contain 2.7-μm superficially-porous-silica particles having an average pore diameter of 450Å. The particles are functionalized with a proprietary polyphenyl bonding process that was specifically designed for LC or LC-MS analyses of intact IgG monoclonal antibodies and their fragments. This Method Validation Kit Part Number contains (3) columns from (3) different manufactured batches. This P/N also includes three vials of the Intact mAb Mass Check Standard (P/N 186006552) and three vials of the mAb Subunit Standard (P/N 186008927).
Separation Mode |
Reversed Phase |
Particle Size |
2.7 µm |
Pore Size |
450 Å |
UNSPSC |
41115709 |
Brand |
BioResolve |
Product Type |
Column Kits |
Units per Package |
3 pk |
BioResolve RP mAb Polyphenyl Method Validation Kit, 450Å, 2.7 µm, 4.6 mm X 100 mm, 3/pk
Extreme chromatographic conditions are often found in reverse-phase analysis of monoclonal antibodies, which means you need an analytical workflow that’s capable of handling those conditions. You get exactly that with the BioResolve RP mAb Polyphenyl Method Validation Kit. Included in this kit are three BioResolve RP mAb Polyphenyl Columns that are specifically designed to provide reverse-phase separations of monoclonal antibodies. Plus, to properly benchmark LC-MS system and instrument performance, we’ve included three vials each of the Intact mAb Mass Check Standard and the mAb Subunit Standard. These helpful quality control reference materials can be used to verify performance before proceeding with your separations. Take your mAb analyses to the next level with the BioResolve RP mAb Polyphenyl Method Validation Kit.
What makes the BioResolve RP mAb Polyphenyl Column well-suited for mAb separations?
For one, the rugged particles inside of the column have been functionalized using a polyphenyl bonding process that makes them perfect for the LC or LC-MS analyses of intact IgG monoclonal antibodies and their fragments. What’s more, each and every BioResolve RP mAb Polyphenyl Column offers the ability to operate at lower temperatures to prevent on-column sample degradation. And to verify column performance before the columns are packed and shipped to you, each columns must undergo a strict QC process with an NIST-based mAb subunit standard.
Validating methods can often be difficult and the last thing you want on your plate is to be a contaminated column. To prevent column contamination, we’re happy to provide a solution with the BioResolve RP mAb Polyphenyl VanGuard Cartridge w/holder. This guard cartridge seamlessly incorporates into your existing workflow to provide enhanced protection from the elements. And because upholding chemical and mechanical stability is always of the utmost importance, this cartridge offers the same inner diameter and pH range as the BioResolve RP mAb Polyphenyl Column.
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What’s the BioResolve RP mAb Polyphenyl Column Specifically Designed For?
The BioResolve RP mAb Polyphenyl Column is specifically designed for the LC or LC-MS analyses of intact IgG monoclonal antibodies and their fragments.