Line drawing of a column

SKU: 176004168
BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 100 mm, 1/pk with Intact mAb and mAb Subunit Standards

BioResolve RP mAb Polyphenyl Columns | 4.6 x 100mm | 176004168


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Product Description

BioResolve RP mAb Columns contain 2.7 µm superficially-porous-silica particles having an average pore diameter of 450 Å. The particles are functionalized with a proprietary polyphenyl bonding process that was specifically designed for LC or LC-MS analyses of intact IgG monoclonal antibodies and their fragments. This p/n: also includes one vial of the Intact mAb Mass Check Standard (p/n: 186006552) and one vial of the mAb Subunit Standard (p/n: 186008927).

Specifications

  • Separation Mode

    Reversed Phase

  • pH Range Min

    2 pH

  • pH Range Max

    7 pH

  • Temperature Limits

    90 C

  • Maximum Pressure

    10000 psi (689 Bar)

  • Particle Size

    2.7 µm

  • Pore Size

    450 Å

  • QC Tested

    Protein

  • System

    HPLC, UHPLC, UPLC

  • USP Classification

    L11

  • Inner Diameter

    4.6 mm

  • Length

    100 mm

  • UNSPSC

    41115709

  • Application

    Protein

  • Brand

    BioResolve

  • Product Type

    Columns

  • Units per Package

    1 pk

Product Support

Documents

Documents



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BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 100 mm, 1/pk with Intact mAb and mAb Subunit Standards

Trying to find a solution for reverse-phase monoclonal antibody analysis?
Look no further than the BioResolve RP mAb Polyphenyl Column, designed specifically for the quantitation of IgG monoclonal antibodies and their fragments. This column can be used on all UHPLC, UPLC and HPLC systems, making it a flexible tool that’s perfect for method development. And if you’re worried about the challenges inherent in biological separations, know that we’ve equipped this column with many features to help you overcome them. Take your analytical workflows to the next level with the help of the BioResolve RP mAb Polyphenyl Column.

At the core of the BioResolve RP mAb Polyphenyl Column is a group of superficially-porous particles that are functionalized by a novel phenyl bonding process that enables this breakthrough separation tool to deliver greater resolution at higher flow rates. When you’re working with incredibly high flow rates and backpressures in UPLC or UHPLC systems, you need an instrument that can withstand those chromatographic conditions. The BioResolve RP mAb Polyphenyl Column offers a maximum pressure limit and wide and usable pH range to meet or exceed those demanding conditions. What’s more, each and every BioResolve RP mAb Polyphenyl Column undergoes strict QC testing before being packed and shipped to you. This is just another way we’re verifying that you only receive the right and best-performing chromatographic instruments right out of the box.

A major consideration when working with biological separations is column fouling over time and after repeated use. Although sample purification protocols remove many of the particulate contaminants that can foul your analytical column, it may not filter them all out, and there’s always a possibility that contaminants show up under high flow rates and backpressures. To meet this consideration, we’ve developed a solution with the BioResolve RP mAb Polyphenyl VanGuard Cartridge. This guard cartridge acts as an extra step for the mobile phase stream to flow through, picking up contaminants and removing them before they reach your analytical column.

Ready to perform successful monoclonal antibody analysis with the BioResolve RP mAb Polyphenyl Column?
Before finalizing your order, shop lab equipment to discover all of the other incredible products and resources we have to offer. Much more than just mAb analysis tools, we offer all of the lab essentials you need to be successful.

Which Separation Mode Does the BioResolve RP mAb Polyphenyl Column Offer?

The BioResolve RP mAb Polyphenyl Column offers a reverse-phase separation mode.