Line drawing of a column

SKU: 176004162
BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 3 mm X 50 mm, 1/pk with Intact mAb and mAb Subunit Standards

BioResolve RP mAb Polyphenyl Column | 176004162


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Product Description

BioResolve RP mAb Columns contain 2.7-μm superficially-porous-silica particles having an average pore diameter of 450Å. The particles are functionalized with a proprietary polyphenyl bonding process that was specifically designed for LC or LC-MS analyses of intact IgG monoclonal antibodies and their fragments. This P/N also includes one vial of the Intact mAb Mass Check Standard (P/N 186006552) and one vial of the mAb Subunit Standard (P/N 186008927).

Specifications

  • Separation Mode

    Reversed Phase

  • Particle Size

    2.7 µm

  • Pore Size

    450 Å

  • UNSPSC

    41115709

  • Brand

    BioResolve

  • Product Type

    Columns

  • Units per Package

    1 pk

Product Support

Documents

Documents



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BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 3 mm X 50 mm, 1/pk with Intact mAb and mAb Subunit Standards

Achieve exceptional chromatographic capabilities with the BioResolve RP mAb Polyphenyl Column, an innovative high-performance liquid chromatography (HPLC) marvel meticulously designed for the precise separation of intact monoclonal antibodies (mAbs) and their subunits. This column, constructed from 450Å porous silica, expertly modified with phenyl groups, excels in retaining mAbs and their subunits with remarkable efficiency. Packed with 2.7 µm particles, it ensures exceptional peak resolution, elevating analytical precision to new heights.

The BioResolve RP mAb Polyphenyl Column offers not only unparalleled performance but also unrivaled convenience. Supplied with intact mAb and mAb subunit standards, researchers gain essential calibration tools to verify the column's performance and guarantee consistent and reliable results. Furthermore, a guard column is thoughtfully provided, safeguarding the main column from potential contamination and enhancing the longevity of your lab equipment.

This column unveils a myriad of applications in the field of mAb analysis. In the characterization of mAbs and their subunits, it delves into the intricacies of their molecular structures, providing vital insights into their properties and functionalities. Purity analysis benefits from the column's exceptional retention capabilities, facilitating accurate determination of mAb composition and ensuring the highest product quality. In aggregation studies, researchers gain valuable data on mAb stability, contributing to the development of safe and effective therapeutic agents. Additionally, the column supports formulation studies, allowing researchers to optimize mAb formulations for enhanced efficacy.

The BioResolve RP mAb Polyphenyl Column boasts compatibility with a diverse range of HPLC systems and detectors, making it a versatile addition to any analytical laboratory. Its stability and reproducible performance ensure that researchers can rely on the column's accuracy and precision, consistently producing trustworthy results. The column can be paired with the BioResolve RP mAb Polyphenyl VanGuard Cartridge w/holder, 450Å, 2.7 µm, 3.9 mm X 5 mm, 3/pk for better performance.

With a particle size of 2.7 µm, an inner diameter of 3 mm, and a length of 50 mm, the column achieves exceptional separation efficiency, unveiling the distinct characteristics of intact mAbs and their subunits. Its 12-month shelf life further supports research continuity, providing ample time for comprehensive analyses.

How do I store the BioResolve RP mAb Polyphenyl Column?

The BioResolve RP mAb Polyphenyl Column should be stored in a cool, dry place. The temperature should be between 5 and 25 degrees Celsius, and the humidity should be below 50%. The column should be stored in its original packaging to protect it from light and moisture.