XBridge BEH C18 XP Column, 130Å, 2.5 µm, 3 mm X 100 mm, 3/pk

The XBridge BEH C18 sorbent can be employed over the whole range of mobile phase pH in HPLC method development. The C18 ligand, on which the XBridge BEH C18 XP Column is based, is trifunctionally linked to provide a universal column for most HPLC separations, with the largest pH range, excellent low pH stability, and ultra-low column bleed. These 2.5 µm eXtended Performance [XP] lab equipment are packed in ultra-low dispersion hardware, providing superior separation performance, resilience, and throughput for HPLC tests while allowing for a smooth transition to UPLC adoption.

To get exceptional chromatographic peaks, use the XBridge BEH C18 XP Column for improved low and high pH stability. The XBridge BEH C18 XP Column circumvents the low-pH instability induced by siloxane bond cleavage via acid hydrolysis by using XBridge Column's proprietary trifunctional bonding and end-capping technology and instead limit the rate of hydrolysis. In comparison to columns packed with monofunctional silane phases, this results in a reduced retention loss. This is true even in low-pH test settings that are expedited.

The ethylene bridges inside the silica matrix of XBridge BEH C18 Column particles resist particle dissolution, eliminating the issues posed by silica-based chromatographic particle failure at increased pH, which results in column voids, efficiency loss, and peak degradation.

The XBridge BEH C18 Columns provide unequaled method development freedom. The lab equipment, which is manufactured in cGMP, ISO9001, and ISO 13485 certified facilities where every step is closely monitored for quality, provide outstanding reproducibility year after year, eliminating the need to test every new batch of columns and preserving long-established methods. The XBridge BEH C18 Columns provide constant column performance and accurate results.

There is virtually no LC/MS leakage in the column thanks to the BEH technology utilized in the XBridge BEH C18 Column, which provides greater hydrolytic stability and particle strength. The XBridge BEH C18 Column eliminates sorbent selection compromises. It allows you to work with any mobile phase, temperature, or pH to accomplish the desired separation.

We recommend that you also invest in the XBridge BEH C18 XP VanGuard Cartridge, 130Å, 2.5 µm, 2.1 mm X 5 mm, 3/pk.