Columns for Antibody Drug Conjugates (ADC)

SKU: 176002152
ACQUITY UPLC CSH Fluoro-Phenyl Column, 130Å, 1.7 µm, 2.1 mm X 50 mm, 3/pk

ACQUITY UPLC CSH Fluoro-Phenyl Column | 176002152


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Product Description

Designed to maximize selectivity differences, the ACQUITY CSH Fluoro-Phenyl column provides maximum method development freedom, especially when using low pH mobile phases. The non-encapped sorbent provides you with enhanced retention of acidic compounds.

Specifications

  • Chemistry

    PFP/Fluoro-Phenyl

  • Separation Mode

    Reversed Phase

  • Particle Substrate

    Hybrid

  • pH Range Min

    1 pH

  • pH Range Max

    8 pH

  • Maximum Pressure

    18000 psi (1240 Bar)

  • Endcapped

    No

  • Bonding Technology

    Fluoro-Phenyl

  • Silanol Activity

    Low

  • Particle Shape

    Spherical

  • Particle Size

    1.7 µm

  • Endfitting Type

    Parker-style

  • Pore Size

    130 Å

  • Format

    Column

  • Surface Area

    185

  • System

    UPLC, UHPLC

  • Particle Technology

    CSH

  • USP Classification

    L43

  • Inner Diameter

    2.1 mm

  • Length

    50 mm

  • Carbon Load

    10 %

  • eCord

    Yes

  • UNSPSC

    41115709

  • Brand

    ACQUITY UPLC

  • Product Type

    Columns

  • Units per Package

    3 pk

Product Support

Documents

Documents



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ACQUITY UPLC CSH Fluoro-Phenyl Column, 130Å, 1.7 µm, 2.1 mm X 50 mm, 3/pk

The ACQUITY UPLC CSH Fluoro-Phenyl Column is designed to increase selectivity differences and enables maximal method development freedom, especially when utilizing low pH mobile phases. The non-end-capped sorbent improves the retention of acidic chemicals.

The ACQUITY UPLC CSH Fluoro-Phenyl Column is an extraordinary piece of laboratory equipment utilized in systems for positional isomer, halogenated compound, and polar compound selectivity. The CSH Fluoro-Phenyl combination, with the specific benefit and combination of Charged Surface Hybrid (CSH) particle technology, aids in offering increased retention of acidic chemicals when compared to typical PFP-bonded stationary phases.

You will notice minimal chromatographic effects with optimized performance when using CSH Fluoro-Phenyl Columns, such as the ACQUITY UPLC CSH Fluoro-Phenyl Column. The ACQUITY UPLC CSH Fluoro-Phenyl Column will allow you to fully utilize CSH Technology. It will offer distinct column selectivity as well as reproducibility. CSH Technology also contributes to the provision of remarkable peak shape and loading capacity for basic chemicals at low and high pH without the use of ion-pair reagents, as well as the system's exceptional stability at low and high pH.

Waters offers a comprehensive line of columns and products with a variety of particle sizes and stationary phases to supplement your laboratory demands and equipment while protecting the physical and chemical composition of your analytical columns. Waters assures that only the highest quality measures and strictest conditions are utilized in the manufacturing of the ACQUITY UPLC CSH Fluoro-Phenyl Column, giving you peace of mind that the lab equipment will not need to be replaced frequently and will provide consistent and accurate results. You can shop for lab equipment on our website based on your laboratory requirements.

You might also want to look into TruView LCMS Certified Clear Glass 12 x 32 mm Screw Neck Vial with Cap and Preslit PTFE/Silicone Septum, 100/pk; TruView LCMS Certified vials are manufactured using highly controlled manufacturing and handling techniques. Mass spectrometers are used to check for cleanliness, and ACQUITY/MS/MS is used to check for low analyte adsorption.

Typically How Much Time Is Required To Change A Column?

In the realm of high-performance liquid chromatography (HPLC), column modifications serve as a practical method development approach, allowing for the flexibility to interchange columns as required. To prevent the accumulation of air at the column entrance, it is advised to securely connect the new column, gradually introducing a gentle flow of solvent from the injector outlet line to fill the column's intake fitting. Prior to sample injection, it is recommended to thoroughly flush the column with a minimum of six column volumes of a new solvent to restore optimal equilibrium. It is customary to disregard the initial injection and focus on subsequent injections, typically the second, third, and subsequent ones, which tend to exhibit reproducible results.