ACQUITY UPLC HSS C18 SB Column, 100Å, 1.8 µm, 2.1 mm X 150 mm, 3/pk

Reduce the risk of technique variation due to inconsistencies in chromatographic media batches or columns. You can rely on the ACQUITY UPLC HSS C18 SB Column to offer consistent results year after year, as the lab equipment was built to deliver reliable and reproducible findings. ACQUITY UPLC HSS C18 SB columns are used for low pH separations that contain complex mixtures of basic and non-basic compounds. Additionally, the ACQUITY HSS C18 SB columns are fully scalable and transferable to HPLC separations.

Use the ACQUITY UPLC HSS C18 SB Column's unique non-end-capped, low-coverage silica-based C18 chemistry to gain alternate selectivity for molecules impacted by silanophilic interactions. Because of secondary interactions with remaining silanols, the lab equipment has a distinctive increased silanol activity, which results in greater retention of basic chemicals. This occurs while non-basic analyte retention is lowered due to low ligand density and ionic repulsion. The ACQUITY UPLC HSS C18 SB Column's unique combination of retention qualities makes it a potent method development tool for imparting changes in Selectivity for Bases (SB) while producing excellent peak shape.

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The ACQUITY UPLC HSS C18 SB Column's packing materials are created exclusively for use with the ACQUITY UPLC System. They are also made in a cGMP-certified, ISO 9001-certified facility using ultra-pure reagents. Each batch of packing material is chromatographically tested with acidic, basic, and neutral analytes, with results held within limited specification ranges to ensure excellent, repeatable performance.

We recommend that you enhance your analytical column’s performance by using the ACQUITY UPLC HSS C18 SB VanGuard Pre-column, 100Å, 1.8 µm, 2.1 mm X 5 mm, 3/pk. Built using the exact same packing materials as the column, the pre-column works in conjunction with the lab equipment and prevents any contaminants from reaching the mobile phase.