Columns for Antibody Drug Conjugates (ADC)

SKU: 176001560
ACQUITY UPLC HSS C18 SB Column, 100Å, 1.8 µm, 2.1 mm X 50 mm, 3/pk

ACQUITY UPLC HSS C18 SB Column | 176001560


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Product Description

ACQUITY UPLC HSS C18 SB columns are used for low pH separations that contain complex mixtures of basic and non-basic compounds. ACQUITY HSS C18 SB columns give you alternative analyte selectivity compared to most modern, high coverage, fully endcapped C18 stationary phases. ACQUITY HSS C18 SB columns are fully scalable and transferable to HPLC separations.

Specifications

  • Chemistry

    C18

  • Separation Mode

    Reversed Phase

  • Particle Substrate

    Silica

  • pH Range Min

    2 pH

  • pH Range Max

    8 pH

  • Temperature Limits

    45 C

  • Maximum Pressure

    18000 psi (1240 Bar)

  • Endcapped

    No

  • Bonding Technology

    C18 SB

  • Silanol Activity

    High

  • Particle Shape

    Spherical

  • Particle Size

    1.8 µm

  • Endfitting Type

    Parker-style

  • Pore Size

    100 Å

  • Format

    Column

  • Surface Area

    230

  • System

    UHPLC, UPLC

  • Particle Technology

    HSS

  • USP Classification

    L1

  • Inner Diameter

    2.1 mm

  • Length

    50 mm

  • Carbon Load

    8.5 %

  • eCord

    Yes

  • UNSPSC

    41115709

  • Brand

    ACQUITY UPLC

  • Product Type

    Columns

  • Units per Package

    3 pk

Product Support

Documents

Documents



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ACQUITY UPLC HSS C18 SB Column, 100Å, 1.8 µm, 2.1 mm X 50 mm, 3/pk

ACQUITY UPLC HSS C18 SB columns are designed for low pH separations of complicated combinations of basic and non-basic chemicals. When compared to the most current, high coverage, fully end-capped C18 stationary phases, ACQUITY HSS C18 SB columns provide alternate analyte selectivity. ACQUITY HSS C18 SB columns are completely scalable and can be used in HPLC separations.

Reduce the probability of technique variation due to inconsistency in chromatographic medium batch or column. Because the ACQUITY UPLC HSS C18 SB Column has been designed to give reliable and reproducible results, you can rely on it to deliver consistent results year after year.

To gain alternative selectivity for compounds impacted by silanophilic interactions, use the ACQUITY UPLC HSS C18 SB Column's unique non-end-capped, low-coverage silica-based C18 chemistry. The lab equipment has a characteristic increased silanol activity as a result of secondary interactions with residual silanols, resulting in greater retention of basic chemicals. This arises as a result of low ligand density and ionic repulsion, which reduces non-basic analyte retention. The unique mix of retention properties in the ACQUITY UPLC HSS C18 SB Column makes it a powerful method development tool capable of imparting changes in Selectivity for Bases (SB) while providing excellent peak shape.

The ACQUITY UPLC HSS C18 SB Column packing materials are created exclusively for use with the ACQUITY UPLC System. They are also manufactured in a cGMP, ISO 9001 certified plant utilizing ultra-pure reagents. Each batch of packing material is chromatographically tested with acidic, basic, and neutral analytes, with the results confined to strict specification ranges to assure exceptional, consistent performance.

Browse our website to shop for lab equipment, examine all products that are compatible with the current offering, or discover additional variations of the same item. The website also contains reference documentation outlining our research and development efforts to assist you in understanding how our equipment operates.

You might also want to look into TruView LCMS Certified Clear Glass 12 x 32 mm Screw Neck Vial, with Cap and Preslit PTFE/Silicone Septum, 2 mL Volume, 100/pk; TruView LCMS Certified vials are manufactured using highly controlled manufacturing and handling techniques. Mass spectrometers are used to check for cleanliness, and ACQUITY/MS/MS is used to check for low analyte adsorption.

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A Quaternary amine is an amine salt in which a nitrogen atom is linked to four groups and has a positive charge. The positively charged surface-active compounds, also known as cationic surfactants, readily bind to the negatively charged surface of most microorganisms. It is utilized as a disinfectant and cleaning agent in a variety of sectors.