XBridge Premier Columns

XBridge Premier Columns

Particle Stability with MaxPeak HPS Protection

Particle Stability with MaxPeak HPS Protection

Working at the extremes of temperature and pH while maximizing analyte peak shape is a significant challenge for methods development scientists. Now, with XBridge Premier UHPLC Columns, it doesn’t have to be.

XBridge Premier Columns prevent undesired analyte/surface interactions through the power of MaxPeak HPS Technology, which is designed to increase analyte recovery, sensitivity, and reproducibility by minimizing analyte/surface interactions that can lead to sample losses.

XBridge Premier Columns are the evolution of Waters XBridge XP (eXtended Performance) columns, and they combine the industry-leading column stability of Ethylene Bridged Hybrid (BEH) particles with MaxPeak High Performance Surfaces (HPS) Technology.

XBridge Premier UHPLC Columns available with MaxPeak and BEH Technologies. XBridge Premier Columns


Introducing MaxPeak Premier SEC Columns for protein analysis.

Improve SEC results on any LC system with minimal method development.

Improve SEC results on any LC system with minimal method development.


XBridge Columns are available in a broad range of sorbent particles and sizes for HPLC, UHPLC.

XBridge Columns are available in a broad range of sorbent particles and sizes for HPLC, UHPLC.

Specifications

Overview

  • Improves analyte sensitivity and peak shapes for more confidence in analytical results
  • Reduces column conditioning and passivation for higher productivity
  • Provides high pH stability and chemical resistance for reliability and longevity
  • Enables maximum method development flexibility
  • Prolongs column lifetimes with optional VanGuard FIT format 

Recommended Use: For method development flexibility with improved analyte peak shape and recovery.


XBridge Premier Column Featured Technologies

XBridge Premier Column Featured Technologies

MaxPeak HPS Technology
  • Reduce analyte/surface interactions
  • Increase analyte recovery
  • Better peak shape
  • Increase sensitivity
BEH Technology
  • Rugged hybrid organic/inorganic base particle
  • Improved peak shape for bases- low silanol activity
  • Wider operating pH range for method development flexibly
  • Mechanical strength for maximum column efficiency at UHPLC operating pressures
VanGuard FIT*
  • All-in-one guard, plus column design
  • Achieve longer column lifetimes
  • Easy installation

* Specific to columns noted with VanGuard FIT

XBridge Premier BEH Column Characteristics

XBridge Premier BEH Column Characteristics

XBridge Premier BEH C18 Columns
  • General purpose reversed-phase C18 Column
  • Superior chemical stability pH 1–12
  • Elevated operating temperature, up to 90 °C
  • Reduction in analyte/surface interactions
  • Excellent pH stability
  • VanGuard FIT Column option
XBridge Premier BEH Shield RP18 Columns
  • Alternative selectivity to traditional alkyl chain C18 columns
  • Improved basic analyte peak shape near neutral pH
  • Compatible with 100% aqueous mobile phases
  • Reduction in analyte/surface interactions
  • VanGuard FIT Column option
XBridge Premier BEH Amide Columns
  • General purpose HILIC column
  • Ideal chemistry for the separation of carbohydrates/saccharides
  • Excellent chemical stability pH 2–11
  • Elevated operating temperature, up to 90 °C
  • Reduction in analyte/surface interactions
  • VanGuard FIT Column option

XBridge Premier BEH-PEO Column Characteristics

XBridge Premier BEH-PEO Column Characteristics

XBridge Premier Protein SEC 250 Å Guards and Columns
  • 2.5 μm particle columns for HPLC and UHPLC separations
  • 250 Å pore size
  • High resolution SEC separations of biomolecules ranging from 10,000 to 650,000 Daltons on any LC system
  • Available SEC Guard Columns to extend analytical SEC Column life
  • Significantly reduce non-desired ionic and hydrophobic secondary interaction for desired SEC platform methods with MaxPeak Premier Technology and BEH-PEO SEC particle technology
  • Specifically designed and QC tested with NIST-based, mAb Size Variant Standard to help ensure batch-to-batch consistency

Mechanical strength and chemical stability

Ethylene Bridged Hybrid (BEH) particle technology ensures maximum column performance and longer column lifetimes under all chromatographic conditions. The hybrid particle technology offers many advantages over conventional silica-based particles, including the ability to control silanol activity for better reproducibility, peak shape, and efficiency. The BEH particle is created from two high purity monomers: tetraethoxysilane (TEOS) and bis(triethoxysilyl) ethane (BTEE), which results in highly stable, mechanically strong particles that set the performance standard for method development.


Cost-effective column protection

VanGuard FIT (Fully Integrated Technology) Guard Columns provide an easy-to-use format that extends the life of your column without sacrificing performance. They thread directly into a FIT column that has been precisely machined to integrate them into the column flow path, eliminating excess volumes. This easy-to-install design does not require ferrules or other small parts.

*XBridge Premier VanGuard FIT Columns are required for use with the XBridge Premier VanGuard FIT Guard Columns, as this is an integrated design requiring the two to thread together.




Resources

Documents

Documents


Support

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Related

Confidently produce the most accurate, reliable, and reproducible data. The Arc Premier System provides right first time robust results from the very first injection, reliably and easily.

Prolong analytical column lifetime while maintaining chromatographic performance with VanGuard Pre-columns and cartridges.

Achieve full method development flexibility with XBridge HPLC/UHPLC Columns designed with BEH technology for stability and lifetime, even in high pH/low pH, high temperatures, and other harsh operating conditions.

Experience the highest level of chromatographic performance, flexibility, and assurance while mitigating unwanted analyte/surface interactions with MaxPeak Premier Columns.

Offers and Discounts

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