Microflow Columns with MaxPeak Premier Technology

Enhanced sensitivity with lower solvent and sample consumption

MaxPeak Premier Microflow Columns are designed to match the industry standard sensitivity and recovery of MaxPeak Premier 2.1 mm ID columns. With unmatched UPLC efficiencies, these new microbore columns enable quantitative bioanalysis, pharma discovery and development groups and omics investigators to gain more data-driven insights, while reducing waste and sample consumption by 4x or more.

MaxPeak Premier Microflow Columns

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View the wide selection of ACQUITY Premier sub-2-µm Column Chemistries and other Nano and Microflow options.

Specifications

Overview

Increase sensitivity and gain greater insight into your sample
Achieve lower limits of detection and quantification
Cut solvent use by 4x or more to support cost and sustainability initiatives
Reduce sample use by 4x or more to get more from volume-limited samples
Enhance speed and productivity with out-of-the-box performance

Recommended Use: Enhance sensitivity of omics studies (i.e., proteomics, metabolomics, or biomarker discovery) and both small- and large-molecule bioanalyses.

Achieve greater insight from comparative omics studies

MaxPeak Premier Microflow 1 mm Columns improve peak shape and resolution of phosphorylated peptides and other acidic analytes when compared to traditional stainless-steel (SS) columns. In a head-to-head analysis, the MaxPeak Premier Peptide BEH C₁₈ Column delivered sharper, higher resolution peaks than a conventional SS 1 mm column.

Improve sensitivity and resolution of small-molecule analytes for metabolomic studies

For acidic small-molecule analytes, like citric acid and iso-citric acid (shown), MaxPeak Premier Microflow Columns demonstrate sharper, taller peaks with up to a 57% increase in peak height, compared to stainless-steel columns.

Reduce solvent and sample consumption

Switching from a 2.1 mm ID column to a 1 mm ID column yields a 4.4x reduction in solvent usage and solvent-related costs per run. With a sample requirement that is 4.4x lower, and no need for sample conditioning, a 1 mm column can also help get the most out of precious volume-limited samples.

Certified for sustainable design

MaxPeak Premier Microflow Columns received an ACT® Label certification for their environmentally responsible design and manufacturing. Produced in a renewable-powered, resource-efficient facility, the columns incorporate 70% recycled content, responsible chemical management practices, and sustainable packaging to minimize their environmental footprint. MaxPeak Premier Microflow Columns are designed to reduce solvent waste while maintaining exceptional analytical quality. By combining sustainability with innovation, MaxPeak Premier Microflow Columns reflect the ongoing commitment by Waters to advancing scientific excellence responsibly.