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CNS Depressants

CNS Depressants
  • Waters Corporation
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Pouring pills in hand with glass of water

This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief highlights the analysis of CNS depressants.

Introduction

Compounds studied in this application brief are shown below.

Experimental

Compounds

Column:

SunFire C18 4.6 x 150 mm, 5.0 μm (p/n: 186002559)

Mobile phase A:

Water

Mobile phase B:

Acetonitrile

Mobile phase C:

2% CH3COOH in water

Flow rate:

1 mL/min

Injection volume:

10 μL

Isocratic Mobile Phase Conditions:

55% A, 35% B, 10% C

Sample concentration:

10 μg/mL in water

Temperature:

30 °C

Detection:

UV @ 254 nm

Instrument:

Alliance 2695 with 2996 PDA

Compounds

Column:

SunFire C8 4.6 x 150 mm, 5.0 μm (p/n: 186002737)

Mobile phase A:

Water

Mobile phase B:

Acetonitrile

Mobile phase C:

2% Acetic acid in water

Flow rate:

1 mL/min

Injection volume:

10 μL

Isocratic Mobile Phase Conditions:

55% A, 35% B, 10% C

Sample concentration:

10 μg/mL in water

Temperature:

30 °C

Detection:

UV @ 254 nm

Instrument:

Alliance 2695 with 2996 PDA

Compounds

Column:

SunFire C8 4.6 x 100 mm, 5.0 μm (p/n: 186002731)

Mobile phase A:

Water

Mobile phase B:

Acetonitrile

Mobile phase C:

2% Acetic acid in water

Flow rate:

1 mL/min

Injection volume:

10 μL

Isocratic Mobile Phase Conditions:

55% A, 35% B, 10% C

Sample concentration:

10 μg/mL in water

Temperature:

30 °C

Detection:

UV @ 254 nm

Instrument:

Alliance 2695 with 2996 PDA

Results and Discussion

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WA41889, March 2005

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