This is an Application Brief and does not contain a detailed Experimental section.
This application brief highlights the impurities profile of Promethazine using SymmetryShield Columns.
Promethazine HCL impurities are studied in this application brief.
            
        | 
                     Column:  | 
                     SymmetryShield RP18, 3.0 x 150 mm, 5 μm (p/n: 186000692)  | 
            
| 
                     Mobile phase A:  | 
                     20 mM potassium phosphate, pH 7.0  | 
            
| 
                     Mobile phase B:  | 
                     Acetonitrile  | 
            
| 
                     Flow rate:  | 
                     1.0 mL/min  | 
            
| 
                     Injection volume:  | 
                     10 μL of 0.5 mg/mL  | 
            
| 
                     Detection:  | 
                     UV @ 254 nm  | 
            
            
        
            
        WA31763.133, June 2003