Scalable reproducibility for deep omics understanding

Scalable reproducibility for deep omics understanding

Deeper biomarker discovery, confident verification, and comprehensive structural characterization are critical for omics analysis. With Waters omics solutions, your lab will get the highest levels of sensitivity, stability, and robustness—all supported by a trusted professional services network, so you can focus on accelerating pioneering science.

With our solutions, analytical scientists can:

  • Maintain biomarker detection performance even under accelerated throughput
  • Support large-cohort omics analysis for phenotyping, toxicology, pharmacology, and systems biology research with confidence
  • Expand services and solutions to relate disease mechanisms to molecular structure and spatial distribution in tissue
  • Increase efficiency and reliability in multi-user, multi-study environments like core labs and translational research centers
Read the Case Study
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Omics performance and speed without compromise

The Xevo MRT Mass Spectrometer is at the heart of Waters discovery omics solutions. Experience 100K FWHM resolution at 100 Hz acquisition speed with Xevo MRT Mass Spectrometer (MS), delivering robust, reproducible, sub-ppm mass accuracy for high-quality omics data matched to all your research needs.

With Xevo MRT MS for your omics analysis, your lab achieves:

  • Maximum acquisition resolution and speed
  • Deepest coverage with maximum confidence
  • Accelerated results with advanced flexible technology
  • A sustainable approach for your future laboratory
  • Spatial omics accessible with DESI XS
Explore Xevo MRT MS

Reproducible metabolomics at scale

Scale up metabolomic and lipidomic research with the sensitivity and dynamic range to realize deep molecular coverage, while maintaining exceptional data quality at a speed enabling even the largest studies.

Waters metabolomics solutions, including Xevo MRT MS, combine exceptional data quality and high-speed analysis with intuitive tools for data export, processing, searching, and visualization of complex datasets, enabling expanded studies without limitations.

 

 

Metabolomics
Targeted Omics
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Linking protein structure with function for structural biology

Better understand disease and inform drug development with insights into complex biological processes from our integrated solution combining ion mobility and high-resolution mass spectrometry with advanced structural biology tools.

Now, your team can achieve structural biology insights never before accessible with precise gas-phase separation and detailed characterization of native-like conformations, folding intermediates, and misfolded states.

The Waters structural biology solution includes:

  • SELECT SERIES Cyclic IMS with IMSn and advanced fragmentation modes, ideally suited for advanced structural protein characterization
  • HDX workflows combining IMS separation and automation for rapid low temperature separations, minimizing error due to back exchange
  • Xevo CDMS instrument for the precise measurement of challenging large and highly heterogeneous molecules
Structural Biology
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The power to translate your discovery

Quantify proteins with unmatched accuracy and consistency with Waters. The Waters integrated solution spans optimized sample prep, industry-leading column chemistry, and advanced LC-MS technology—simplifying complex workflows and delivering sensitive, scalable measurements.

Targeted Omics and Biomarker Quantification
Quantum computing accelerating drug discovery

Spatial omics in high definition

Unlock the power of MS imaging (MSI) with a suite of an integrated tools that turn surfaces and tissues into high-definition molecular maps.

Achieve accurate insights at every stage of your research with Waters future-ready MS solutions, powered by MALDI and DESI ionization, intuitive informatics, responsive service, and expert applications.

  • End-to-end spatial omics coverage, from discovery of unknown molecular profiles to targeted biomarker quantification
  • Accelerated high-resolution molecular imaging with DESI XS and Xevo MRT. This powerful combination delivers exceptional DESI sensitivity at speed, ideal for discovery imaging of low-abundant species
  • Deeper biological insights with complementary MALDI and DESI imaging on SELECT SERIES MRT, provide multi-layered spatial data, minimal prep, and repeated analysis from a single tissue section
  • Clarity without complexity with HDI Software, which unifies acquisition, processing, and visualization aligning MALDI, DESI, and optical images
  • Achieve ultimate specificity by combining DESI XS and SELECT SERIES Cyclic IMS, resolving isomers and structural interferences in MSI
  • Utilize the high-sensitivity of Xevo TQ Absolute XR and DESI XS for efficient detection and targeted quantification of known biomarkers and metabolites, ideal for large studies, multimodal workflows, and sustainable laboratory operations
MS Imaging Solutions
Cell liver imaging

Find out how Waters omics solutions can transform your lab workflows today.

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