• Application Note

Verapamil and Norverapamil

Verapamil and Norverapamil
  • Waters Corporation
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Verapamil molecular structure

This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief demonstrates analysis of verapamil and norverapamil.

Introduction

The compounds used in this study are – 

Compounds 

USP Tailing Factors

Norverapamil

1.1

Verapamil

1.06

Methoxyverapamil (I.S.)

1.07

Experimental

HPLC Method

Column:

Symmetry Shield RP8, 3.9 x 150 mm, 5 μm

Part numbers:

WAT200655

Mobile phase:

50 mM phosphate pH 7.0/acetonitrile/methanol 41:37:22

Flow rate:

1.0 mL/min

Injection volume:

40 μL

Detection:

UV @ 230 nm

Results and Discussion

Featured Products

WA31763.178, June 2003

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