• Application Note

Naproxen – SymmetryShield RP18

Naproxen – SymmetryShield RP18
  • Waters Corporation
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This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief highlights the analysis of naproxen using SymmetryShield RP18.

Introduction

Compounds used in this application brief are Naproxen and Butyrophenone.

Experimental

HPLC Method

Column:

SymmetryShield RP18, 4.6 x 250 mm, 5 μm (p/n: 186000112)

Mobile phase:

Acetonitrile/water 46:54, 2.0 mL of glacial acetic acid in 1 L of mobile phase

Flow rate:

1.0 mL/min

Injection volume:

20 μL

Detection:

UV @ 254 nm

USP tailing factors:

1. 1.09

2. 1.13

Results and Discussion

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WA31763.111, June 2003

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