- Endotoxin testing — Consistent orbital mixing at controlled speeds for sensitive endotoxin testing assays
- ELISA and plate-based immunoassays — Uniform mixing for antibody-antigen binding and washing steps across the full microplate
- Cell-based assays — Gentle, vibration-free mixing that maintains cell viability during plate setup
Shaker+ Connected Device
Shaker+ Connected Device
High-performance orbital shaker technology
High-performance orbital shaker technology
Your lab workflows often require thorough mixing for applications like dilutions, resuspending samples, and incubations. Shaker+ Connected Devices deliver precise, repeatable, and traceable sample mixing for a variety of applications, such as endotoxin testing, protein or nucleic acid extraction, general bioanalytical and quality control (QC) sample prep, and more. Controlled and monitored through OneLab Software, Shaker+ Connected Devices, available in two convenient formats, enable remote set-up, execution, and documentation as part of your digital SOPs and automated workflows with the Andrew+ Robot.
Shaker+ Connected Devices offer:
Vibration-free orbital shaking
OneLab Software-connected operation for digital control and traceability
Remote set-up and monitoring to reduce error
Easy integration into Andrew+ Robot automated workflows
Shaker+ Connected Device
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Maximum operating altitude |
2000 m |
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User interface |
OneLab software |
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Dimensions (W x L x H) |
170 x 162 x 100 mm (The specified dimensions are subject to change according to the labware) |
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External power supply |
Input 100–240 VAC, 1.4 A; output 24 VDC, 5 A, 120 W |
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Operating voltage |
24 VDC |
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Pollution degree of the intended environment |
Pollution degree 2 |
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Warranty |
1 year |
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Relative humidity |
80% at 37 °C |
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Environment temperature operating range |
+4 to +37 °C |
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Protection class |
IP20 |
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Weight |
2.55 kg |
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Power or current rating |
5A |
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Overvoltage category DC port |
Cat I |
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Network connectivity |
Gigabit Ethernet / Wi-Fi 2.4 GHz and 5 GHz |
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Cleaning |
Only with a wet tissue or isopropanol |
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Certification |
CE, FCC, RoHS, WEEE |
Specifications
Overview
- Connect to OneLab Software by Wi-Fi/Ethernet for remote control and tracking
- Achieve vibration-free motion for the highest mixing speeds on the market, ranging from 200 to 3000 rpm (Microplate Shaker+ Device) and 200 to 2000 rpm (Tube Shaker+ Device), with an orbit of 2 mm
- Maintain gentle mixing of samples by planar orbital motion
- Available for both microplates (Microplate Shaker+ Device) and tubes (Tube Shaker+ Device)
- Designed for use with the Andrew+ Robot
- Microplate Shaker+ benefits from an automatic microplate positioning system that enables precise manipulation of consumables by the Andrew+ Robot for accurate and repeatable pipetting
Recommended Use: Precise, repeatable sample mixing for automated bioanalytical workflows.
Two convenient mixing formats
The Microplate Shaker+ Device delivers high-speed, vibration-free orbital mixing up to 3000 rpm for microplates, with a growing range of compatible labware used directly on the platform or via dedicated racks. The Tube Shaker+ Device delivers vibration-free orbital mixing up to 2000 rpm for commonly used tube formats, with speed and mixing profiles controlled and recorded in OneLab Software for consistent sample homogenization.
Accommodates a variety of workflows
Lab workflows can require thorough mixing or homogenization steps for applications like dilutions, resuspending samples, and incubations. It can be difficult to achieve reproducible results across operators, and there is no easy way of accomplishing streamlined method transfer and scale up when automation is required. Using the Shaker+ Device directly during manual method validations gives you an automatable solution from the start – with no need to revalidate or redesign methods for automation. The device is ideal for several workflows, including:
Endotoxin testing (e.g., LAL-based assays)
ELISA and other plate-based immunoassays
Sample resuspension and homogenization (cells, beads, pellets)
Protein extraction and digestion workflows
Nucleic acid extraction and clean-up
General bioanalytical and QC sample preparation
Applications
- Peptide reconstitution — Dissolving dried or lyophilized peptide samples in injection solvent to ensure complete and reproducible reconstitution before LC-MS
- Amino acid analysis — Reproducible mixing during derivatization and preparation steps
- Protein precipitation — Thorough mixing of crash solvents (acetonitrile, methanol) with protein samples for clean-up prior to LC-MS analysis
- Magnetic bead resuspension (SP3 / SPRI) — Consistent resuspension of paramagnetic beads during solid-phase-enhanced sample preparation (SP3) workflows for protein binding, washing, and elution at room temperature
- Sample resuspension and homogenization — High-speed vibration-free mixing for cells, beads, and pellets
- Serial dilutions — Consistent mixing between dilution steps, reducing operator-to-operator variability
- General bioanalytical and QC sample prep — Standardized, documented mixing across operators and labs
Resources
Documents
Documents
What do you want to do?
What do you want to do?
Need Help?
Frequently Asked Questions
Frequently Asked Questions
What are the key benefits of Shaker+?
- Traceability — Every mixing parameter (speed, duration, timing, labware ID) is automatically recorded in OneLab Software. No manual logbooks — just a complete, audit-ready trail.
- Reproducibility — OneLab sets all parameters remotely with ±25 RPM accuracy at 1 RPM resolution, eliminating operator-dependent variability.
- Productivity — Remote setup and monitoring remove bench trips. When paired with Pipette+ or Andrew+ Robot, mixing steps trigger automatically within the protocol.
- Automation Readiness — Microplate Shaker+ includes automatic positioning for robotic pipetting access. Same device, same protocol from manual to automated — zero re-validation.
Which lab scenarios are ideal for Shaker+?
- Compliance-driven workflows — Replace untracked shakers with a connected device that logs every mixing action automatically, giving QA and auditors the digital record they need.
- Multi-step assays where mixing consistency affects results — Workflows like ELISA, endotoxin testing, and nucleic acid extraction get vibration-free orbital mixing controlled by OneLab — consistent across operators, runs, and labs.
- Manual-to-automation transition — Validate your method at the bench with Shaker+ today, then transfer the same protocol to Andrew+ tomorrow — same device, same protocol, no re-validation needed.
What are the traceability, compliance, and integration benefits?
Traceability and Compliance
- Automated logging of every speed setpoint, duration, start/stop timestamp, and labware ID — no manual entries.
- Digital protocols replace paper records with auditable electronic workflows.
- Supports GxP, GLP/GMP, and 21 CFR Part 11 requirements.
- Mixing data captured alongside pipetting (Pipette+ / Andrew+) and temperature data (Peltier+ / Heater-Shaker+) in a single unified digital record.
Software Integration
- OneLab + Empower — Links sample prep (including mixing steps) to chromatography workflows with GxP-compliant audit trails.
- OneLab + MassLynx — Exports sample lists and triggers LC–MS runs from mixing-dependent prep.
- OneLab + waters_connect — Closes the loop from preparation to analytical result in a single traceable workflow.
These integrations ensure mixing steps are seamlessly linked to downstream analytical execution with full traceability.
What applications are ideal for Shaker+?
Shaker+ supports any workflow where mixing consistency and documentation directly affect results:
- Endotoxin testing — Precise orbital mixing for reproducible LAL-based assays
- ELISA and plate-based immunoassays — Uniform mixing for consistent antibody-antigen binding and wash steps
- Sample resuspension and homogenization — Vibration-free mixing without disrupting sample integrity
- Protein extraction and digestion — Consistent mixing during enzymatic workflows like tryptic digestion
- Nucleic acid extraction and clean-up — Gentle resuspension of magnetic beads and purification reagents
- Serial dilutions — Consistent mixing eliminates operator-to-operator variability
- Amino acid analysis — Reproducible mixing during derivatization and preparation steps
- General bioanalytical and QC sample prep — Standardized, documented mixing supporting regulatory compliance
Also applicable across genomics, proteomics, drug discovery, and clinical research.
Can I use Shaker+ without Andrew+ Robot?
Yes. Shaker+ connects directly to OneLab Software via Wi-Fi or Ethernet as a fully standalone connected device. OneLab still provides full remote control and complete traceability — no Andrew+ Robot required.
How does Shaker+ connect to my network?
Shaker+ connects to OneLab Software via Wi-Fi (2.4/5 GHz dual-band) or Gigabit Ethernet. Set parameters, monitor status, and review logs from any browser-compatible device on the same network — no dedicated software installation required.
Related
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