• Application Note

Amoxapine and Trazodone

Amoxapine and Trazodone
  • Waters Corporation
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This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief highlights the analysis of amoxapine and trazodone using Symmetry C8 columns.

Introduction

Compounds studied in this study are Amoxapine and Trazodone.

Experimental

HPLC Method

Column:

Symmetry C8, 3.9 x 150 mm, 5 μm (p/n: WAT046970)

Guard Column:

Sentry Guard Column 3.9 x 20 mm, 5 μm (p/n: WAT054250)

Mobile phase:

20 mM potassium phosphate pH 7.0/ methanol 35:65

Flow rate:

1.0 mL/min

Injection volume:

10 μL of 100 μg/mL amoxapine and 100 μg/mL trazodone

Detection:

UV @ 254 nm

USP Tailing Factors

1. 1.1
2. 1.4 

Results and Discussion

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WA31763.21, June 2003

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